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Kiyotake Suenaga

Original Papers

  1. Hideo Kigoshi, Makoto Ojika, Kiyotake Suenaga, Tsuyoshi Mutou, Junko Hirano, Akira Sakakura, Takeshi Ogawa, Masanori Nisiwaki, and Kiyoyuki Yamada:
    Synthetic Studies on Aplyronine A, a Potent Antitumor Substance of Marine Origin: Stereocontrolled Synthesis of the C21-C34 Segment
    Tetrahedron Lett. 1994, 35 (8), 1247―1250.
  2. Hideo Kigoshi, Makoto Ojika, Takeshi Ishigaki, Kiyotake Suenaga, Tsuyoshi Mutou, Akira Sakakura, Takeshi Ogawa, and Kiyoyuki Yamada:
    Total Synthesis of Aplyronine A, a Potent Antitumor Substance of Marine Origin
    J. Am. Chem. Soc. 1994, 116 (16), 7443―7444.
  3. Kiyotake Suenaga, Takeshi Ishigaki, Akira Sakakura, Hideo Kigoshi, and Kiyoyuki Yamada:
    Absolute Stereochemistry and Synthesis of Aplyronines B and C, the Congeners of Aplyronine A, a Potent Antitumor Substance of Marine Origin
    Tetrahedron Lett. 1995, 36 (28), 5053―5056.
  4. Hideo Kigoshi, Kiyotake Suenaga, Tsuyoshi Mutou, Takeshi Ishigaki, Toshiyuki Atsumi, Hiroyuki Ishiwata, Akira Sakakura, Takeshi Ogawa, Makota Ojika, and Kiyoyuki Yamada:
    Aplyronine A, a Potent Antitumor Substance of Marine Origin, Aplyronines B and C, and Artificial Analogues: Total Synthesis and Structure-Cytotoxicity Relationships
    J. Org. Chem. 1996, 61 (16), 5326―5351.
  5. Kiyotake Suenaga, Hideo Kigoshi, and Kiyoyuki Yamada:
    Auripyrones A and B, Cytotoxic Polypropionates from the Sea Hare Dolabella auricularia: Isolation and Structures
    Tetrahedron Lett. 1996, 37 (29), 5151―5154.
  6. Kiyotake Suenaga, Tsuyoshi Mutou, Takunobu Shibata, Takashi Itoh, Hideo Kigoshi, and Kiyoyuki Yamada:
    Isolation and Stereostructure of Aurilide, a Novel Cyclodepsipeptide from the Japanese Sea Hare Dolabella auricularia
    Tetrahedron Lett.     1996, 37 (37), 6771―6774.
  7. Kiyotake Suenaga, Noriyuki Kamei, Youko Okugawa, Masaki Takagi, Atsushi Akao, Hideo Kigoshi, and Kiyoyuki Yamada:
    Cytotoxicity and Actin Depolymerizing Activity of Aplyronine A, a Potent Antitumor Macrolide of Marine Origin, and the Natural and Artificial Analogs
    Bioorg. Med. Chem. Lett. 1997, 7 (3), 269―274.
  8. Tsuyoshi Mutou, Kiyotake Suenaga, Tatsuya Fujita, Takashi Itoh, Noboru Takada, Kozue Hayamizu, Hideo Kigoshi, and Kiyoyuki Yamada:
    Enantioselective Synthesis of Aurilide, a Cytotoxic 26-membered Cyclodepsipeptide of Marine Origin
    Synlett 1997 (2), 199―201.
  9. Kiyotake Suenaga, Tomohiro Nagoya, Takunobu Shibata, Hideo Kigoshi, and Kiyoyuki Yamada:
    Dolabelides C and D, Cytotoxic Macrolides from the Sea Hare Dolabella auricularia
    J. Nat. Prod. 1997, 60 (2), 155―157.
  10. Hiroki Sone, Kiyotake Suenaga, Yuhki Bessho, Takashi Kondo, Hideo Kigoshi, and Kiyoyuki Yamada:
    Synthesis of Aglycon of the Aurisides A and B, Cytotoxic Macrolide Glycosides of Marine Origin
    Chem. Lett. 1998, (1), 85―86.
  11. Kiyotake Suenaga, Takunobu Shibata, Noboru Takada, Hideo Kigoshi, and Kiyoyuki Yamada:
    Aurilol, a Cytotoxic Bromotriterpene Isolated from the Sea Hare Dolabella auricularia
    J. Nat. Prod. 1998, 61 (4), 515―518.
  12. Kiyotake Suenaga, Susumu Kokubo, Chikara Shinohara, Tomoko Tsuji, and Daisuke Uemura:
    Structures of Amamistatins A and B, Novel Growth Inhibitors of Human Tumor Cell Lines from an Actinomycete
    Tetrahedron Lett. 1999, 40 (10), 1945―1948.
  13. Noboru Takada, Hiroko Sato, Kiyotake Suenaga, Hirokazu Arimoto, Kaoru Yamada, Katsuhiro Ueda, and Daisuke Uemura:
    Isolation and Structures of Haterumalides NA, NB, NC, ND, and NE, Novel Macrolides from an Okinawan Sponge Ircinia sp.
    Tetrahedron Lett. 1999, 40 (34), 6309-6312.
  14. Noboru Takada, Kiyotake Suenaga, Kaoru Yamada, Shu-zhen Zheng, Hai-sheng Chen, and Daisuke Uemura:
    Isolation and Structures of Attenols A and B. Novel Bicyclic Triols from the Chinese Bivalve Pinna attenuata
    Chem. Lett.     1999, (10), 1025-1026.
  15. Kiyotake Suenaga, Sachiko Aoyama, Wang Xi, Hirokazu Arimoto, Kohji Yamaguchi, Kaoru Yamada, Tomoko Tsuji, Akihiro Yamada, and Daisuke Uemura:
    Isolation and Structure of Kasarin, a Novel Azetinone Compound, Isolated from a Marine Microoorganism
    Heterocycles 2000, 52 (3), 1033-1036.
  16. Noboru Takada, Masato Iwatsuki, Kiyotake Suenaga, Daisuke Uemura:
    Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata
    Tetrahedron Lett.     2000, 41 (33), 6425-6428.
  17. Susumu Kokubo, Kiyotake Suenaga, Chikara Shinohara, Tomoko Tsuji, and Daisuke Uemura:
    Structures of Amamistatins A and B, Novel Growth Inhibitors of Human Tumor Cell Lines from Nocardia asteroides
    Tetrahedron     2000, 56 (35), 6435-6440.
  18. Susumu Kokubo, Kentaro Yogi, Md. Jasim Uddin, Toshiyasu Inuzuka, Kiyotake Suenaga, Katsuhiro Ueda, and Daisuke Uemura:
    Kohamaic Acids A and B, Novel Cytotoxic Sesterterpenic Acids, from the Marine Sponge Ircinia sp.
    Chem. Lett. 2001, (2), 176-177.
  19. Md. Jasim Uddin, Susumu Kokubo, Kiyotake Suenaga, Katsuhiro Ueda, and Daisuke Uemura:
    Haterumaimides A-E, Five New Dichlorolissoclimide-type Diterpenoids from an Ascidian, Lissoclinum sp.
    Heterocycles 2001, 54 (2), 1039-1047.
  20. Noboru Takada, Masami Watanabe, Akihiro Yamada, Kiyotake Suenaga, Kaoru Yamada, Katsuhiro Ueda, and Daisuke Uemura:
    Isolation and Structures of Haterumadioxins A and B, Cytotoxic Endoperoxides from the Okinawan Sponge Plakortis lita
    J. Nat. Prod    . 2001, 64 (3), 356-359.
  21. Kiyotake Suenaga, Keisuke Araki, Tetsuya Sengoku, and Daisuke Uemura:
    Enantioselective Synthesis of Attenols A and B
    Org. Lett. 2001, 3 (4), 527-529.
  22. Noboru Takada, Naoyoshi Umemura, Kiyotake Suenaga, Tong Chou, Akito Nagatsu, Takeharu Haino, Kaoru Yamada, and Daisuke Uemura:
    Pinnatoxins B and C, the most toxic components in the pinnatoxin series from the Okinawan bivalve Pinna muricata
    Tetrahedron Lett. 2001, 42 (20), 3491-3494.
  23. Noboru Takada, Naoyoshi Umemura, Kiyotake Suenaga, and Daisuke Uemura:
    Structural determination of pteriatoxins A, B and C, extremely potent toxins from the bivalve Pteria penguin
    Tetrahedron Lett. 2001, 42 (20), 3495-3497.
  24. Noboru Takada, Reiko Watanabe, Kiyotake Suenaga, Kaoru Yamada, and Daisuke Uemura:
    Isolation and Structures of Hedaols A, B, and C, New Bisnorditerpenes from a Japanese Brown Alga
    J. Nat. Prod. 2001, 64 (5), 653-655.
  25. Noboru Takada, Reiko Watanabe, Kiyotake Suenaga, Kaoru Yamada, Katsuhiro Ueda, Masaki Kita and Daisuke Uemura:
    Zamamistatin, a significant antibacterial bromotyrosine derivative, from the Okinawan sponge Pseudoceratina purpurea
    Tetrahedron Lett. 2001, 42 (31), 5265-5267.
  26. Noboru Takada, Masami Watanabe, Kiyotake Suenaga, Kaoru Yamada, Masaki Kita and Daisuke Uemura:
    Isolation and structures of hedathiosulfonic acids A and B, novel thiosulfonic acids from the deep-sea urchin Echinocardium cordatum
    Tetrahedron Lett. 2001, 42 (37), 6557-6560.
  27. Kiyotake Suenaga, Hiroki Shimogawa, Satoru Nakagawa, and Daisuke Uemura:
    Catharsitoxins from the Chinese remedy qiung laug
    Tetrahedron Lett. 2001, 42 (40), 7079-7081.
  28. Hideo Kigoshi, Takashi Itoh, Takafumi Ogawa, Kenya Ochi, Mayuko Okada, Kiyotake Suenaga, and Kiyoyuki Yamada:
    Auriculol, a cytotoxic oxygenated squalene from the Japanese sea hare Dolabella auricularia: isolation, stereostructure, and synthesis
    Tetrahedron Lett. 2001, 42 (42), 7461-7464.
  29. Toshiaki Teruya, Kiyotake Suenaga, Tomoyuki Koyama, Yoshikatsu Nakano, and Daisuke Uemura:
    Arachidonic acid and α-linolenic acid, feeding attractants for the crown-of-thorns sea star Acanthaster planci, from the sea urchin Toxopneustes pileolus.
    J. Exp. Mar. Biol. Ecol. 2001, 266 (2), 123-134.
  30. M. Jasim Uddin, Susumu Kokubo, Katsuhiro Ueda, Kiyotake Suenaga, and Daisuke Uemura:
    Haterumamides F-I, Four New Cytotoxic Diterpene Alakaloids from an Ascidian Lissoclinum Species.
    J. Nat. Prod. 2001, 64 (9), 1169-1173.
  31. Toshiaki Teruya, Satoru Nakagawa, Tomoyuki Koyama, Kiyotake Suenaga, and Daisuke Uemura:
    Terpiodiene, a Novel Tricyclic Alcohol from the Okinawan Sponge Terpios hoshinota
    Chem. Lett.     2002, (1), 38-39.
  32. Hideo Kigoshi, Kiyotake Suenaga, Masaki Takagi, Atsushi Akao, Kengo Kanematsu, Noriyuki Kamei, Youko Okugawa, and Kiyoyuki Yamada:
    Cytotoxicity and actin-depolymerizing activity of aplyronine A, a potent antitumor macrolide of marine origin, and its analogs
    Tetrahedron 2002, 58 (6), 1075-1102.
  33. Keisuke Araki, Kiyotake Suenaga, Tetsuya Sengoku, and Daisuke Uemura:
    Total synthesis of attenols A and B
    Tetrahedron 2002, 58 (10), 1983-1995.
  34. Masaki Kita, Masami Watanabe, Noboru Takada, Kiyotake Suenaga, Kaoru Yamada, and Daisuke Uemura:
    Hedathiosulfonic acids A and B, novel thiosulfonic acids from the deep-sea urchin Echinocardium cordatum
    Tetrahedron 2002, 58 (32), 6405-6412.
  35. M. Jasim Uddin, Susumu Kokubo, Katsuhiro Ueda, Kiyotake Suenaga, and Daisuke Uemura:
    Haterumaimides J and K, potent cytotoxic diterpene alkaloids from the ascidian Lissoclinum species
    Chem. Lett. 2002, (10), 1028-1029.
  36. Toshiaki Teruya, Satoru Nakagawa, Tomoyuki Koyama, Kiyotake Suenaga, Kita, Masaki, and Daisuke Uemura:
    Nakiterpiosin, a novel cytotoxic C-nor-D-homosteroid from the Okinawan sponge Terpios hoshinota
    Tetrahedron Lett. 2003, 44 (28), 5171-5173.
  37. Hideo Kigoshi, Takao Ichino, Noboru Takada, Kiyotake Suenaga, Akihiro Yamada, Kaoru Yamada, and Daisuke Uemura:
    Isolation of Tribromoacetamide from an Okinawan Alga and Biological Activities of Its Analogs
    Chem. Lett. 2004, 33 (2), 98-99.
  38. Kiyotake Suenaga, Hidenari Hori, Hitoshi Ishida, Haruo Nukaya, Rodney D Roberts, and Kuniro Tsuji:
    Inducing substance for abalone larval metamorphosis from the crustose coralline alga, Hydrolithon samoense
    Fisheries Science, 2004, 70 (2), 342-344.
  39. Kiyotake Suenaga, Saori Miya, Takeshi Kuroda, Tomohisa Handa, Kengo Kanematsu, Akira Sakakura, and Hideo Kigoshi:
    Synthesis and actin-depolymerizing activity of mycalolide analogs
    Tetrahedron Lett., 2004, 45 (28), 5383-5386.
  40. Kiyotake Suenaga, Yui Takayanagi, Masashi Yamaura, and Hideo Kigoshi:
    Total Synthesis of (-)-ent-Jolkinolide D
    Chem. Lett. 2004, 33 (7), 918-919.
  41. Kiyotake Suenaga, Tsuyoshi Mutou, Takunobu Shibata, Takashi Itoh, Tatsuya Fujita, Noboru Takada, Kozue Hayamizu, Masaki Takagi, Taiji Irifune, Hideo Kigoshi, and Kiyoyuki Yamada:
    Aurilide, a cytotoxic depsipeptide from the sea hare Dolabella auricularia: isolation, structure determination, synthesis, and biological activity
    Tetrahedron 2004, 60 (38), 8509-8527.
  42. Toshiaki Teruya, Hiroki Shimogawa, Kiyotake Suenaga, and Hideo Kigoshi:
    Biselides A and B, Novel Macrolides from the Okinawan Ascidian Didemnidae sp.
    Chem. Lett. 2004, 33 (9), 1184-1185.
  43. Keiko Kobayashi, Hiroki Shimogawa, Akira Sakakura, Toshiaki Teruya, Kiyotake Suenaga, and Hideo Kigoshi:
    Spongiacysteine, a Novel Cysteine Derivative from the Marine Sponge Spongia sp.
    Chem. Lett. 2004, 33 (10), 1262-1263.
  44. Kazushi Watanabe, Yuto Suzuki, Kenta Aoki, Akira Sakakura, Kiyotake Suenaga, and Hideo Kigoshi:
    Formal Synthesis of Optically Active Ingenol via Ring-Closing Olefin Metathesis
    J. Org. Chem., in press.

Books and Reviews

  1. Kiyoyuki Yamada, Makoto Ojika, Hideo Kigoshi, and Kiyotake Suenaga:
    Cytotoxic Substances from Opisthobranch Mollusks
    N. Fusetani (Ed.), Drugs from the Sea, S. Karger AG. Basel, 2000, pp. 59―73.
  2. Kiyotake Suenaga:
    Bioorganic Studies on Marine Natural Products with Bioactivity, Such as Antitumor Activity and Feeding Attractance
    Bull. Chem. Soc. Jpn., 77, 443-451 (2004).

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