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Hideo Kigoshi

Original Papers

  1. Hideo Kigoshi, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    Laurencenyne, a Plausible Precursor of Various Nonterpenoid C15-Compounds, and Neolaurencenyne from the Red Alga Laurencia okamurai.
    Tetrahedron Lett., 22 (47), 4729-4732 (1981).
  2. Hideo Kigoshi, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    Isolation and Structures of trans-Laurencenyne, a Possible Precursor of the C15 Halogenated Cyclic Ethers, and trans-Neolaurencenyne from Laurencia okamurai.
    Tetrahedron Lett., 23 (14), 1475-1476 (1982).
  3. Hideo Kigoshi, Makoto Ojika, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    (10R,11R)-(+)-Squalene-10,11-epoxide: Isolation from Laurencia okamurai and the Asymmetric Synthesis.
    Tetrahedron Lett., 23 (51), 5413-5414 (1982).
  4. Haruki Niwa, Kazumasa Wakamatsu, Tsuneaki Hida, Kenji Niiyama, Hideo Kigoshi, Mayumi Yamada, Hiroshi Nagase, Masaaki Suzuki, and Kiyoyuki Yamada:
    Stereocontrolled Total Synthesis of (-)-Picrotoxinin and (+)-Coriamyrtin via a Common Isotwistane Intermediate.
    J. Am. Chem. Soc., 106 (16), 4547-4552 (1984).
  5. Kazumasa Wakamatsu, Hideo Kigoshi, Kenji Niiyama, Haruki Niwa, and Kiyoyuki Yamada:
    Stereocontrolled Total Synthesis of (+)-Tutin, a Toxic Sesquiterpene of Picrotoxane-Type.
    Tetrahedron Lett., 25 (35), 3873-3874 (1984).
  6. Iwao Hirono, Kiyoyuki Yamada, Haruki Niwa, Yoshikazu Shizuri, Makoto Ojika, Shigetoshi Hosaka, Taketo Yamaji, Kazumasa Wakamatsu, Hideo Kigoshi, Kenji Niiyama, and Youichi Uosaki:
    Separation of Carcinogenic Fraction of Bracken Fern.
    Cancer Lett., 21, 239-246 (1984).
  7. Iwao Hirono, Y. Kono, K. Takahashi, Kiyoyuki Yamada, Haruki Niwa, Makoto Ojika, Hideo Kigoshi, Kenji Niiyama, and Y. Uosaki:
    Reproduction of Acute Bracken Poisoning in a Calf with Ptaquiloside, a Bracken Constituent.
    Veterinary Record, 115, 375-378 (1984).
  8. Iwao Hirono, Shigetoshi Aiso, Taketo Yamaji, Hideki Mori, Kiyoyuki Yamada, Haruki Niwa, Makoto Ojika, Kazumasa Wakamatsu, Hideo Kigoshi, Kenji Niiyama, and Youichi Uosaki:
    Carcinogenicity in Rats of Ptaquiloside Isolated from Bracken.
    Gann, 75 (10), 833-836 (1984).
  9. Hideki Mori, Shigeyuki Sugie, Iwao Hirono, Kiyoyuki Yamada, Haruki Niwa, Makoto Ojika, Kazumasa Wakamatsu, and Hideo Kigoshi:
    Genotoxicity of Ptaquiloside, a Bracken Carcinogen, in the Hepatocyte Primary Culture/DNA-Repair Test.
    Mutation Res., 143, 75-78 (1985).
  10. Makoto Ojika, Hideo Kigoshi, Hiroki Kuyama, Haruki Niwa, and Kiyoyuki Yamada:
    Studies on Pteridium aquilinum var. latiusculum, IV. Isolation of Three p-Hydroxystyrene Glycosides and an Efficient Method for the Isolation of Ptaquiloside, an Unstable Bracken Carcinogen.
    J. Nat. Prod., 48 (4), 634-637 (1985).
  11. Hideo Kigoshi, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    Four New C15 Acetylenic Polyenes of Biogenetic Significance from the Red Alga Laurencia okamurai: Structures and Synthesis.
    Tetrahedron, 42 (14), 3781-3787 (1986).
  12. Hideo Kigoshi, Makoto Ojika, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    Isolation of (10R,11R)-(+)-Squalene-10,11-epoxide from the Red Alga Laurencia okamurai and Its Enantioselective Synthesis.
    Tetrahedron, 42 (14), 3789-3792 (1986).
  13. Kazumasa Wakamatsu, Hideo Kigoshi, Kenji Niiyama, Haruki Niwa, and Kiyoyuki Yamada:
    Stereocontrolled Total Synthesis of (+)-Tutin and (+)-Asteromurin A, Toxic Picrotoxane Sesquiterpenes.
    Tetrahedron, 42 (20), 5551-5558 (1986).
  14. Hideo Kigoshi, Yoshifumi Imamura, Haruki Niwa, and Kiyoyuki Yamada:
    Total Synthesis of Ptaquilosin: The Aglycon of Ptaquiloside, a Potent Bracken Carcinogen.
    J. Am. Chem. Soc., 111 (6), 2302-2303 (1989).
  15. Hideo Kigoshi, Akihiko Sawada, Yoshisuke Nakayama, Haruki Niwa, and Kiyoyuki Yamada:
    Stereocontrolled Total Synthesis of (±)-Ptaquilosin, the Aglycone of Ptaquiloside, a Bracken Carcinogen.
    Tetrahedron Lett., 30 (15), 1983-1986 (1989).
  16. Hideo Kigoshi, Akihiko Sawada, Haruki Niwa, and Kiyoyuki Yamada:
    Synthesis of a Functionalized Carbocyclic Skeleton of Ptaquilosin, the Aglycone of a Bracken Carcinogen Ptaquiloside Based on an Intramolecular Diels-Alder Reaction.
    Bull. Chem. Soc. Jpn., 62 (5), 1639-1642 (1989).
  17. Hideo Kigoshi, Akihiko Sawada, Yoshifumi Imamura, Haruki Niwa, and Kiyoyuki Yamada:
    Ptaquilosin, the Aglycone of a Bracken Carcinogen Ptaquiloside: Chemical Derivation from Ptaquiloside and the Reactivity.
    Tetrahedron, 45 (9), 2551-2556 (1989).
  18. Hideo Kigoshi, Yoshifumi Imamura, Kohji Yoshikawa, and Kiyoyuki Yamada:
    Three New Cytotoxic Alkaloids, Aplaminone, Neoaplaminone and Neoaplaminone Sulfate from the Marine Mollusc Aplysia kurodai.
    Tetrahedron Lett., 31 (34), 4911-4914 (1990).
  19. Hideo Kigoshi, Haruki Niwa, Kiyoyuki Yamada, Thomas J. Stout, and Jon Clardy:
    The Three-Dimensional Structure of Neohalicholactone, an Unusual Fatty Acid Metabolite from the Marine Sponge Halichondria okadai Kadota.
    Tetrahedron Lett., 32 (22), 2427-2428 (1991).
  20. Hideo Kigoshi, Yoshifumi Imamura, Kohji Yoshikawa, Haruki Niwa, and Kiyoyuki Yamada:
    Factors That Cause Contrasteric Alkylation of a Cyclopentane-1,2-dicarboxylic Acid Monoester.
    Tetrahedron Lett., 32 (35), 4541-4544 (1991).
  21. Hideo Kigoshi, Yoshifumi Imamura, Akihiko Sawada, Haruki Niwa, and Kiyoyuki Yamada:
    Novel Transformation of Formyl Groups into Hydroxyl Groups Utilizing Deformylative Autoxidation of Aldehydes.
    Bull. Chem. Soc. Jpn., 64 (12), 3735-3737 (1991).
  22. E. J. Corey and Hideo Kigoshi:
    A Route for the Enantioselective Total Synthesis of Antheridic Acid, the Antheridium-Inducing Factor from Anemia phyllitidis.
    Tetrahedron Lett., 32 (38), 5025-5028 (1991).
  23. Hideo Kigoshi, Yuichi Adachi, Kohji Yoshikawa, and Kiyoyuki Yamada:
    Absolute Stereochemistry of Aplaminone and Neoaplaminone, Cytotoxic Bromodopamines from a Marine Mollusc: Enantioselective Synthesis of Debromoneoaplaminone.
    Tetrahedron Lett., 33 (29), 4195-4198 (1992).
  24. Makoto Ojika, Hideo Kigoshi, Kohji Yoshikawa, Yoshisuke Nakayama, and Kiyoyuki Yamada:
    A New Bromo Diterpene, epi-Aplysin-20, and ent-Isoconcinndiol from the Marine Mollusc Aplysia kurodai.
    Bull. Chem. Soc. Jpn., 65 (8), 2300-2302 (1992).
  25. Hideo Kigoshi, Hideyuki Tanaka, Junichi Hirokawa, Kazuhiro Mizuta, and Kiyoyuki Yamada:
    Synthesis of Analogues of a Bracken Ultimate Carcinogen and Their DNA Cleaving Activities.
    Tetrahedron Lett., 33 (44), 6647-6650 (1992).
  26. Iwao Hirono, Mitsuya Ito, Shigeru Yagyu, Masanobu Higa, Kazumasa Wakamatsu, Teruaki Kishikawa, Osamu Nishikawa, Kiyoyuki Yamada, Makoto Ojika, and Hideo Kigoshi:
    Reproduction of Progressive Retinal Degeneration (Bright Blindness) in Sheep by Administration of Ptaquiloside Contained in Bracken.
    J. Vet. Med. Sci., 55 (6), 979-983 (1993).
  27. Hideo Kigoshi, Yoshifumi Imamura, Kazuhiro Mizuta, Haruki Niwa, and Kiyoyuki Yamada:
    Total Synthesis of Natural (-)-Ptaquilosin, the Aglycon of a Potent Bracken Carcinogen Ptaquiloside, and the (+)-Enantiomer and Their DNA Cleaving Activities.
    J. Am. Chem. Soc., 115 (8), 3056-3065 (1993).
  28. Makoto Ojika, Hideo Kigoshi, Takeshi Ishigaki, and Kiyoyuki Yamada:
    Further Studies on Aplyronine A, an Antitumor Substance Isolated from the Sea Hare Aplysia kurodai.
    Tetrahedron Lett., 34 (52), 8501-8504 (1993).
  29. Makoto Ojika, Hideo Kigoshi, Takeshi Ishigaki, Masanori Nisiwaki, Itaru Tsukada, Kazuhiro Mizuta, and Kiyoyuki Yamada:
    Studies on the Stereochemistry of Aplyronine A: Determination of the Stereochemistry of the C21-C34 Fragment.
    Tetrahedron Lett., 34 (52), 8505-8508 (1993).
  30. Tatsushi Kushida, Motonari Uesugi, Yukio Sugiura, Hideo Kigoshi, Hideyuki Tanaka, Junichi Hirokawa, Makoto Ojika, and Kiyoyuki Yamada:
    DNA Damage by Ptaquiloside, a Potent Carcinogen: Detection of Selective Strand Breaks and Identification of DNA Cleavage Products.
    J. Am. Chem. Soc., 116 (2), 479-486 (1994).
  31. Hideo Kigoshi, Makoto Ojika, Kiyotake Suenaga, Tsuyoshi Mutou, Junko Hirano, Akira Sakakura, Takeshi Ogawa, Masanori Nisiwaki, and Kiyoyuki Yamada:
    Synthetic Studies on Aplyronine A a Potent Antitumor Substance of Marine Origin: Stereocontrolled Synthesis of the C21-C34 Segment.
    Tetrahedron Lett., 35 (8), 1247-1250 (1994).
  32. Makoto Ojika, Hideo Kigoshi, Takeshi Ishigaki, Itaru Tsukada, Takaya Tuboi, Takeshi Ogawa, and Kiyoyuki Yamada:
    Absolute Stereochemistry of Aplyronine A, a Potent Antitumor Substance of Marine Origin.
    J. Am. Chem. Soc., 116 (16), 7441-7442 (1994).
  33. Hideo Kigoshi, Makoto Ojika, Takeshi Ishigaki, Kiyotake Suenaga, Tsuyoshi Mutou, Akira Sakakura, Takeshi Ogawa, and Kiyoyuki Yamada:
    Total Synthesis of Aplyronine A, a Potent Antitumor Substance of Marine Origin.
    J. Am. Chem. Soc., 116 (16), 7443-7444 (1994).
  34. Hiroyuki Ishiwata, Hiroki Sone, Hideo Kigoshi, and Kiyoyuki Yamada:
    Total Synthesis of Doliculide, a Potent Cytotoxic Cyclodepsipeptide from the Japanese Sea Hare Dolabella auricularia.
    J. Org. Chem., 59 (17), 4712-4713 (1994).
  35. Hiroyuki Ishiwata, Hiroki Sone, Hideo Kigoshi, and Kiyoyuki Yamada:
    Enantioselective Total Synthesis of Doliculide, a Potent Cytotoxic Cyclodepsipeptide of Marine Origin and Structure-Cytotoxicity Relationships of Synthetic Doliculide Congeners.
    Tetrahedron, 50 (45), 12853-12882 (1994).
  36. Kiyotake Suenaga, Takeshi Ishigaki, Akira Sakakura, Hideo Kigoshi, and Kiyoyuki Yamada:
    Absolute Stereochemistry and Synthesis of Aplyronines B and C, the Congeners of Aplyronine A, a Potent Antitumor Substance of Marine Origin.
    Tetrahedron Lett., 36 (28), 5053-5056 (1995).
  37. Hideo Kigoshi, Misako Niwa, Hidekazu Ohashi, Hideyuki Tanaka, Junichi Hirokawa, Hiroyuki Ishiwata, and Kiyoyuki Yamada:
    Synthesis of Bracken Ultimate Carcinogen Analogues Possessing a DNA Binding Moiety and Their DNA Cleaving Activities.
    Tetrahedron Lett., 36 (30), 5349-5352 (1995).
  38. Kiyotake Suenaga, Hideo Kigoshi, and Kiyoyuki Yamada:
    Auripyrones A and B, Cytotoxic Polypropionates from the Sea Hare Dolabella auricularia: Isolation and Structures.
    Tetrahedron Lett., 37 (29), 5151-5154 (1996).
  39. Hideo Kigoshi, Kiyotake Suenaga, Tsuyoshi Mutou, Takeshi Ishigaki, Toshiyuki Atsumi, Hiroyuki Ishiwata, Akira Sakakura, Takeshi Ogawa, Makoto Ojika, and Kiyoyuki Yamada:
    Aplyronine A, a Potent Antitumor Substance of Marine Origin, Aplyronines B and C, and Artificial Analogues: Total Synthesis and Structure-Cytotoxicity Relationships.
    J. Org. Chem., 61 (16), 5326-5351 (1996).
  40. Kiyotake Suenaga, Tsuyoshi Mutou, Takunobu Shibata, Takeshi Itoh, Hideo Kigoshi, and Kiyoyuki Yamada:
    Isolation and Stereostructure of Aurilide, a Novel Cyclodepsipeptide from the Japanese Sea Hare Dolabella auricularia.
    Tetrahedron Lett., 37 (37), 6771-6774 (1996).
  41. Shin-ya Saito, Shugo Watabe, Hiroshi Ozaki, Hideo Kigoshi, Kiyoyuki Yamada, Nobuhiro Fusetani, and Hideaki Karaki:
    Novel Actin Depolymerizing Macrolide Aplyronine A.
    J. Biochem., 120 (3), 552-555 (1996).
  42. Tsuyoshi Mutou, Takashi Kondo, Takunobu Shibata, Makoto Ojika, Hideo Kigoshi, and Kiyoyuki Yamada:
    Synthesis of Dolastatin G and Nordolastatin G, Cytotoxic 35-Membered Cyclodepsipeptides of Marine Origin.
    Tetrahedron Lett., 37 (40), 7299-7302 (1996).
  43. Hiroki Sone, Hideo Kigoshi, and Kiyoyuki Yamada:
    Aurisides A and B, Cytotoxic Macrolide Glycosides from the Japanese Sea Hare Dolabella auricularia.
    J. Org. Chem., 61 (25), 8956-8960 (1996).
  44. Kiyotake Suenaga, Noriyuki Kamei, Youko Okugawa, Masaki Takagi, Atsushi Akao, Hideo Kigoshi, and Kiyoyuki Yamada:
    Cytotoxicity and Actin Depolymerizing Activity of Aplyronine A, a Potent Antitumor Macrolide of Marine Origin, and the Natural and Artificial Analogs.
    Bioorg. Med. Chem. Lett., 7 (3), 269-274 (1997).
  45. Tsuyoshi Mutou, Kiyotake Suenaga, Tatsuya Fujita, Takashi Itoh, Noboru Takada, Kozue Hayamizu, Hideo Kigoshi, and Kiyoyuki Yamada:
    Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin.
    Synlett, (2), 199-201 (1997).
  46. Kiyotake Suenaga, Tomohiro Nagoya, Takunobu Shibata, Hideo Kigoshi, and Kiyoyuki Yamada:
    Dolabelides C and D, Cytotoxic Macrolides Isolated from the Sea Hare Dolabella auricularia.
    J. Natl. Prod., 60 (2), 155-157 (1997).
  47. Hideo Kigoshi, Yuusi Kitamura, Tatsuya Fujita, Hidekazu Ohashi, Toshiyuki Atsumi, Junko Takagi, Tsuyoshi Mutou, Kiyoyuki Yamada, Tetsuya Kusakabe, Daisuke Sasaki, and Yukio Sugiura:
    A New Synthetic Analogue of the Bracken Ultimate Carcinogen: Elevation of Stability and Alteration of DNA Alkylation Site Selectivity.
    Tetrahedron Lett., 38 (18), 3235-3238 (1997).
  48. Hiroki Sone, Hideo Kigoshi, and Kiyoyuki Yamada:
    Isolation and Stereostructure of Dolastatin I, a Cytotoxic Cyclic Hexapeptide from the Japanese Sea Hare Dolabella auricularia.
    Tetrahedron, 53 (24), 8149-8154 (1997).
  49. Hiroki Sone, Kiyotake Suenaga, Yuhki Bessho, Takashi Kondo, Hideo Kigoshi, and Kiyoyuki Yamada:
    Synthesis of the Aglycon of Aurisides A and B, Cytotoxic Macrolide Glycosides of Marine Origin.
    Chem. Lett., (1), 85-86 (1998).
  50. Kiyotake Suenaga, Noboru Takada, Takunobu Shibata, Hideo Kigoshi, and Kiyoyuki Yamada:
    Aurilol, a Cytotoxic Bromotriterpene Isolated from the Sea Hare Dolabella auricularia.
    J. Nat. Prod., 61 (4), 515-518 (1998).
  51. Hideo Kigoshi, Kengo Kanematsu, and Daisuke Uemura:
    Turbotoxins A and B, Novel Diiodotyramine Derivatives from the Japanese Gastropod Turbo marmorata.
    Tetrahedron Lett., 40 (31), 5745-5748 (1999).
  52. Hideo Kigoshi and Shiho.Yamada:
    Synthesis of Dolastatin I, a Cytotoxic Cyclic Hexapeptide from the Sea Hare Dolabella auricularia.
    Tetrahedron, 55 (42), 12301-12308 (1999).
  53. Hideo Kigoshi, Yuto Suzuki, Kenta Aoki, and Daisuke Uemura:
    Synthetic Studies of Ingenol: Synthesis of in,out-Tricyclo[7.4.1.01,5]tetradecan-14-one.
    Tetrahedron Lett., 41 (20), 3927-3930 (2000).
  54. Hideo Kigoshi, Kengo Kanematsu, Kyoko Yokota, and Daisuke Uemura:
    Turbotoxins A and B, Novel Diiodotyramine Derivatives from the Japanese Gastropod Turbo marmorata.
    Tetrahedron, 56 (46), 9063-9070 (2000).
  55. Hideo Kigoshi, Takao Ichino, Kaoru Yamada, Yasuharu Ijuin, Solange Fumi Makita, and Daisuke Uemura:
    Stereostructure and Bioactivities of Jolkinolide D.
    Chem. Lett., 2001 (6), 518-519 (2001).
  56. Masaki Kita, Hideo Kigoshi, and Daisuke Uemura:
    Isolation and Structure of Korolkoside, a Bis-Iridoid Glucoside from Lonicera korolkovii.
    J. Nat. Prod., 64 (8), 1090-1092 (2001).
  57. Hideo Kigoshi, Takashi Itoh, Takafumi Ogawa, Kenya Ochi, Mayuko Okada, Kiyotake Suenaga, and Kiyoyuki Yamada:
    Auriculol, a Cytotoxic Oxygenated Squalene from the Japanese Sea Hare : Isolation, Stereostructure, and Synthesis.
    Tetrahedron Lett., 42 (42), 7461-7464 (2001).
  58. Hideo Kigoshi, Norimitsu Hayashi, and Daisuke Uemura:
    Stereoselective Synthesis of Pinnamine, an Alkaloidal Marine Toxin from Pinna muricata.
    Tetrahedron Lett., 42 (42), 7469-7471 (2001).
  59. Hideo Kigoshi, Kiyotake Suenaga, Masaki Takagi, Atsushi Akao, Kengo Kanematsu, Noriyuki Kamei, Youko Okugawa, and Kiyoyuki Yamada:
    Cytotoxicity and Actin-Depolymerizing Activity of Aplyronine A, a Potent Antitumor Macrolide of Marine Origin, and Its Analogs.
    Tetrahedron, 58 (6), 1075-1102 (2002).
  60. Akira Sakakura, Yui Takayanagi, and Hideo Kigoshi:
    Jolkinolide D Pharmacophore: Synthesis and Reaction with Amino Acids, Nucleosides, and DNA.
    Tetrahedron Lett., 43 (34), 6055-6058 (2002).
  61. Hideo Kigoshi, Masaki Kita, Seiji Ogawa, Masahiro Itoh, and Daisuke Uemura:
    Enantioselective Synthesis of 15-epi-Haterumalide NA Methyl Ester and Revised Structure of Haterumalide NA.
    Org. Lett., 5 (6), 957-960 (2003).
  62. Hideo Kigoshi, Takao Ichino, Noboru Takada, Kiyotake Suenaga, Akihiro Yamada, Kaoru Yamada, and Daisuke Uemura:
    Isolation of Tribromoacetamide from an Okinawan Alga and Biological Activities of Its Analogs.
    Chem. Lett., 33 (2), 98-99 (2004).
  63. Hiroki Shimogawa, Youngjoo Kwon, Qian Mao, Yoshinori Kawazoe, Yongmun Choi, Shinichi Asada, Hideo Kigoshi, and Motonari Uesugi:
    A Wrench-shaped Synthetic Molecule That Modulates a Transcription Factor-Coactivator Interaction.
    J. Am. Chem. Soc., 126 (11), 3461-3471 (2004).
  64. Kiyotake Suenaga, Saori Miya, Takeshi Kuroda, Tomohisa Handa, Kengo Kanematsu, Akira Sakakura, and Hideo Kigoshi:
    Synthesis and actin-depolymerizing activity of mycalolide analogs
    Tetrahedron Lett., 45 (28), 5383-5386 (2004).
  65. Kiyotake Suenaga, Yui Takayanagi, Masashi Yamaura, and Hideo Kigoshi:
    Total Synthesis of (-)-ent-Jolkinolide D
    Chem. Lett., 33 (7), 918-919 (2004).
  66. Toshiaki Teruya, Hiroki Shimogawa, Kiyotake Suenaga, and Hideo Kigoshi:
    Biselides A and B, Novel Macrolides from the Okinawan Ascidian Didemnidae sp.
    Chem. Lett., 33 (9), 1184 -1185 (2004).
  67. Akira Sakakura, Yui Takayanagi, Hiroki Shimogawa, and Hideo Kigoshi:
    Jolkinolide D Pharmacophore: Synthesis and Reaction with Amino Acids, Nucleosides, and DNA.
    Tetrahedron, 60 (33), 7067-7075 (2004).
  68. Kiyotake Suenaga, Tsuyoshi Mutou, Takunobu Shibata, Takashi Itoh, Tatsuya Fujita, Noboru Takada, Kozue Hayamizu, Masaki Takagi, Taiji Irifune, Hideo Kigoshi, and Kiyoyuki Yamada:
    Aurilide, a cytotoxic depsipeptide from the sea hare Dolabella auricularia: isolation, structure determination, synthesis, and biological activity
    Tetrahedron, 60 (38), 8509-8527 (2004).
  69. Keiko Kobayashi, Hiroki Shimogawa, Akira Sakakura, Toshiaki Teruya, Kiyotake Suenaga, and Hideo Kigoshi.
    Spongiacysteine, a Novel Cysteine Derivative from the Marine Sponge Spongia sp.
    Chem. Lett., 33 (10), 1262 -1263 (2004).
  70. Kazushi Watanabe, Yuto Suzuki, Kenta Aoki, Akira Sakakura, Kiyotake Suenaga, and Hideo Kigoshi.
    Formal Synthesis of Optically Active Ingenol via Ring-Closing Olefin Metathesis.
    J. Org. Chem., 69 (23), 7802-7808 (2004).
  71. Toshiaki Teruya, Keiko Kobayashi, Kiyotake Suenaga, and Hideo Kigoshi:
    Phormidinines A and B, Novel 2-Alkylpyridine Alkaloids from the Cyanobacterium Phormidium sp.,
    Tetrahedron Lett., 46 (23), 4001-4003 (2005).
  72. Toshiaki Teruya, Kiyotake Suenaga, Sakiko Maruyama,Mineko Kurotakiand, and Hideo Kigoshi:
    Biselides A-E: Novel Polyketides from the Okinawan Ascidian Didemnidae sp.,
    Tetrahedron, 61 (27), 6561-6567 (2005).
  73. Hiroki Shimogawa, Toshiaki Teruya, Kiyotake Suenaga, and Hideo Kigoshi:
    Isolation of Two 13-epi-Neoverrucosane-Type Diterpenoids from a Marine Sponge Axinyssa tethyoides,
    Bull. Chem. Soc. Jpn., 78 (7), 1345-1347 (2005).
  74. Shinya Nomoto and Hideo Kigoshi:
    GC/MS Analysis of Maleimides in Present Sediments and of Those Produced by Chromic Acid Oxidation of Neogene Sedimentary Rocks,
    Research of Organic Geochemistry, 20, 31-37 (2005).
  75. Ichiro Hayakawa, Toshiaki Teruya, and Hideo Kigoshi:
    Revised Structure of Zamamistatin,
    Tetrahedron Lett., 47 (1), 155-158 (2006).
  76. Hiroki Shimogawa, Satomi Kuribayashi, Toshiaki Teruya, Kiyotake Suenaga and Hideo Kigoshi:
    Cinachyramine, the Novel Alkaloid Possessing a Hydrazone and Two Aminals from Cinachyrella sp.,
    Tetrahedron Lett., 47 (9), 1409-1411 (2006).
  77. Toshiaki Teruya, Keiko Kobayashi, Kiyotake Suenaga, and Hideo Kigoshi:
    Cyclohaliclonamines A-E: Dimeric, Trimeric, Tetrameric, Pentameric, and Hexameric 3-Alkyl Pyridinium Alkaloids from a Marine Sponge Haliclona sp.,
    J. Nat. Prod., 69 (1), 135-139 (2006).
  78. Kunio Hirata, Shin Muraoka, Kiyotake Suenaga, Takeshi Kuroda, Kenichi Kato, Hiroshi Tanaka, Masaki Yamamoto, Masaki Takata, Kiyoyuki Yamada, and Hideo Kigoshi:
    Structure Basis for Antitumor Effect of Aplyronine A,
    J. Mol. Biol., 356 (4), 945-954 (2006).
  79. Takeshi Kuroda, Kiyotake Suenaga, Akira Sakakura, Tomohisa Handa, Kazuhito Okamoto, and Hideo Kigoshi:
    Study of the Interaction between Actin and Antitumor Substance Aplyronine A with a Novel Fluorescent Photoaffinity Probe,
    Bioconjugate Chem., 17 (2), 524-529 (2006).
  80. Keiko Kobayashi, Toshiaki Teruya, Kiyotake Suenaga, Yoko Matsui, Hideki Masuda, and Hideo Kigoshi:
    Isotheasaponins B1-B3 from Camellia sinensis var. sinensis Tea Leaves,
    Phytochemistry, 67 (13), 1385-1389 (2006).
  81. Kiyotake Suenaga, Hiroshi Hoshino, Takanori Yoshii, Kazunori Mori, Hiroki Sone, Yuhki Bessho, Akira Sakakura, Ichiro Hayakawa, Kiyoyuki Yamada and Hideo Kigoshi:
    Enantioselective Synthesis of Aurisides A and B, Cytotoxic Macrolide Glycosides of Marine Origin,
    Tetrahedron, 62 (33), 7687-7698 (2006).
  82. Kiyotake Suenaga, Tomoyuki Kimura, Takeshi Kuroda, Keita Matsui, Saori Miya, Satomi Kuribayashi, Akira Sakakura, and Hideo Kigoshi:
    Synthesis and Biological Activity of Mycalolide Analogs,
    Tetrahedron, 62 (35), 8278-8290 (2006).
  83. Makoto Ojika, Hideo Kigoshi, Yoshifumi Yoshida, Takeshi Ishigaki, Masanori Nisiwaki, Itaru Tsukada, Masayuki Arakawa, Hisao Ekimoto, and Kiyoyuki Yamada:
    Aplyronine A, a Potent Antitumor Macrolide of Marine Origin, and the Congeners Aplyronines B and C: Isolation, Structures, and Bioactivities,
    Tetrahedron, 63 (15), 3138-3167 (2007).
  84. Ichiro Hayakawa, Yuki Asuma, Takayuki Ohyoshi, Kenta Aoki, and Hideo Kigoshi:
    Synthetic Study on 13-Oxyingenol: Construction of the Full Carbon Framework,
    Tetrahedron Lett., 48 (35), 6221-6224 (2007).
  85. Ichiro Hayakawa, Akiyuki Ikedo, and Hideo Kigoshi:
    Synthesis of Glaziovianin A, a Potent Antitumor Isoflavone,
    Chemistry Lett., 36 (11), 1382-1383 (2007).
  86. Tomoyuki Kimura, Satomi Kuribayashi, Tetsuya Sengoku, Keita Matsui, Shoko Ueda, Ichiro Hayakawa, Kiyotake Suenaga, and Hideo Kigoshi:
    Synthetic Studies on Mycalolide B: Synthesis of the C7-C35 Fragment,
    Chemistry Lett., 36 (12), 1490-1491 (2007).
  87. Takahiro Miyake, Hideo Kigoshi, and Hiroyuki Akita:
    Chemoenzymatic Synthesis of (+)-Totarol, (+)-Podototarin, (+)-Sempervirol, and (+)-Jolkinolides E and D,
    Tetrahedron: Asymmetry, 18 (24), 2915-2922 (2007).
  88. Takeshi Kuroda and Hideo Kigoshi:
    Aplaminal: A Novel Cytotoxic Aminal Isolated from the Sea Hare Aplysia kurodai,
    Org. Lett., 10 (3), 489-491 (2008).
  89. Ichiro Hayakawa, Mitsuru Ueda, Masashi Yamaura, Yoichi Ikeda, Yuta Suzuki, Kensaku Yoshizato, and Hideo Kigoshi:
    Second-Generation Total Synthesis of Haterumalide NA Using B-Alkyl Suzuki-Miyaura Coupling,
    Org. Lett., 10 (9), 1859-1862 (2008).
  90. Shinya Nomoto, Mitsuru Satou, Takahiro Yoshida, Hajime Mita, Gen Kumagai, Kouichi Nomoto, Hideo Kigoshi, and Yuichiro Kashiyama:
    The First Experimental Demonstration of Benzoporphyrin Formation from Sedimentary Porphyrins,
    Chemistry Lett., 37 (5), 490-491 (2008).
  91. Kiyotake Suenaga, Shuri Kajiwara, Satomi Kuribayashi, Tomohisa Handa, and Hideo Kigoshi:
    Synthesis and Cytotoxicity of Aurilide Analogs,
    Bioorg. Med. Chem. Lett., 18 (14), 3902-3905 (2008).
  92. Ichiro Hayakawa, Hidekazu Watanabe, and Hideo Kigoshi:
    Synthesis of Ustalic Acid, an Inhibitor of Na+,K+-ATPase,
    Tetrahedron, 64 (25), 5873-5877 (2008).
  93. Masaki Kita, Yuta Tsunematsu, Ichiro Hayakawa, and Hideo Kigoshi:
    Structure of Zamamistatin - a correction,
    Tetrahedron Lett., 49 (37), 5383-5384 (2008).
  94. Tetsuya Sengoku, Takuma Takemura, Emi Fukasawa, Ichiro Hayakawa, and Hideo Kigoshi:
    Aldol-type Reaction of a 4-Pyrone: a Straightforward Approach to 4-Pyrone-containing Natural Products,
    Tetrahedron Lett., 50 (3), 325-328 (2009).
  95. Kazuhiro Kitamura, Toshiaki Teruya, Takeshi Kuroda, Hideo Kigoshi, and Kiyotake Suenaga:
    Synthesis of Actin-depolymerizing Compounds,
    Bioorg. Med. Chem. Lett., 19 (7), 1896-1898 (2009).
  96. Takashi Yoshizumi, Akio Ohno, Tomohiro Tsujita, Hirobumi Takahashi, Osamu Okamoto, Ichiro Hayakawa, and Hideo Kigoshi:
    Practical Syntheses of Optically Pure Key Intermediates of Opioid Receptor-like 1 (ORL1) Antagonists.
    Synthesis, 2009 (7), 1153-1163.
  97. Mitsuru Ueda, Masashi Yamaura, Yoichi Ikeda, Yuta Suzuki, Kensaku Yoshizato, Ichiro Hayakawa, and Hideo Kigoshi:
    Total Synthesis and Cytotoxicity of Haterumalides NA and B and their Artificial Analogs.
    J. Org. Chem., 74 (9), 3370-3377 (2009).
  98. Dongju Jung, Hiroki Shimogawa, Youngjoo Kwon, Qian Mao, Shin-ichi Sato, Shinji Kamisuki, Hideo Kigoshi, and Motonari Uesugi:
    Wrenchnolol Derivative Optimized for Gene Activation in Cells,
    J. Am. Chem. Soc., 131 (13), 4774-4782 (2009).
  99. Yoko Matsui, Keiko Kobayashi, Hideki Masuda, Hideo Kigoshi, Makoto Akao, Hidetoshi Sakurai, and Hitomi Kumagai:
    Quantitative Analysis of Saponins in a Tea-leaf Extract and Their Antihypercholesterolemic Activity,
    Biosci. Biotechnol. Biochem., 73 (7), 1513-1519 (2009).
  100. Masaki Kita, David StC. Black, Osamu Ohno, Kaoru Yamada, Hideo Kigoshi, and Daisuke Uemura:
    Duck-Billed Platypus Venom Peptides Induce Ca2+ Influx in Neuroblastoma Cells,
    J. Am. Chem. Soc., 131 (50), 18038-18039 (2009).

Reviews and Books in English

  1. Kiyoyuki Yamada and Hideo Kigoshi:
    Bioactive Compounds from the Sea Hares of Two Genera: Aplysia and Dolabella.
    Bull. Chem. Soc. Jpn., 70 (7), 1479-1489 (1997).
  2. Kiyoyuki Yamada, Makoto Ojika, and Hideo Kigoshi:
    Isolation, Chemistry, and Biochemistry of Ptaquiloside, a Bracken Carcinogen.
    Angew. Chem., 110 (13/14), 1918-1926 (1998); Angew. Chem. Int. Ed. Engl., 37 (13/14), 1818-1826 (1998).
  3. Kiyoyuki Yamada, Makoto Ojika, Hideo Kigoshi, and Kiyotake Suenaga:
    "Cytotoxic Substances from Opisthobranch Mollusks,"
    in "Drugs from the Sea," ed by N. Fusetani, S. Karger AG, Basel, pp. 59-73 (2000).
  4. Kiyoyuki Yamada, Makoto Ojika, and Hideo Kigoshi:
    Ptaquiloside, the Major Toxin of Bracken, and Related Terpene Glycosides: Chemistry, Biology and Ecology,
    Nat. Prod. Rep., 24 (4), 798-813 (2007).
  5. Hideo Kigoshi and Ichiro Hayakawa:
    Marine Cytotoxic Macrolides Haterumalides and Biselides, and Related Natural Products,
    Chemical Record, 7, 254-264 (2007).
  6. Kiyoyuki Yamada, Makoto Ojika, Hideo Kigoshi, and Kiyotake Suenaga:
    Aplyronine A, a Potent Antitumour Macrolide of Marine Origin, and the Congeners Aplyronines B-H: Chemistry and Biology,
    Nat. Prod. Rep., 26 (1), 27-43 (2009).
(January, 2010)

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