Kenji IWASAKI

Biochemistry(Structural Biology and Chemistry)

Professor ：　PhD. 1998, Osaka University

　TEL +81-29-853-6045　

Structural analysis of biological molecules, particularly proteins and nucleic acids to elucidate their functions and design drug based on their structures.　A wide variety of methods are used such as electron cryo-microscopy, x-ray crystallography, biochemistry and molecular biology.

◇Malay AD, Miyazaki N, Biela A, Chakraborti S, Majsterkiewicz K, Stupka I, Kaplan CS, Kowalczyk A, Piette BMA G, Hochberg GKA, Wu D, Wrobel TP, Fineberg A, Kushwah M, Kelemen M, Vavpetic P, Pelicon P, Kukura P, Benesch JLP, Iwasaki K, Heddle JG. An ultra-stable gold-coordinated protein cage displaying reversible assembly and paradoxical geometry, Nature, 2019, doi: 10.1038/s41586-019-1185-4.
◇Tsutsumi K, Yonehara R, Ishizaka-Ikeda E, Miyazaki N, Maeda S, Iwasaki K, Nakagawa A, Yamashita E. Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism, Nature Commun. 2019, 10, 1520. DOI: 10.1038/s41467-019-09463-9.
◇Matsumoto A, Miyazaki N, Takagi J, Iwasaki K. 2D hybrid analysis: Approach for binding three-dimensional atomic model by electron microscopy image matching. 2017. Sci. Rep. 7, 377: DOI: 10.1038/s41598-017-00337-y.