論文リスト (Publication List)

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木越英夫 (Hideo Kigoshi)

原著論文

  1. Hideo Kigoshi, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    Laurencenyne, a Plausible Precursor of Various Nonterpenoid C15-Compounds, and Neolaurencenyne from the Red Alga Laurencia okamurai,
    Tetrahedron Lett., 22 (47), 4729-4732 (1981).
  2. Hideo Kigoshi, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    Isolation and Structures of trans-Laurencenyne, a Possible Precursor of the C15 Halogenated Cyclic Ethers, and trans-Neolaurencenyne from Laurencia okamurai,
    Tetrahedron Lett., 23 (14), 1475-1476 (1982).
  3. Hideo Kigoshi, Makoto Ojika, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    (10R,11R)-(+)-Squalene-10,11-epoxide: Isolation from Laurencia okamurai and the Asymmetric Synthesis,
    Tetrahedron Lett., 23 (51), 5413-5414 (1982).
  4. Haruki Niwa, Kazumasa Wakamatsu, Tsuneaki Hida, Kenji Niiyama, Hideo Kigoshi, Mayumi Yamada, Hiroshi Nagase, Masaaki Suzuki, and Kiyoyuki Yamada:
    Stereocontrolled Total Synthesis of (-)-Picrotoxinin and (+)-Coriamyrtin via a Common Isotwistane Intermediate,
    J. Am. Chem. Soc., 106 (16), 4547-4552 (1984).
  5. Kazumasa Wakamatsu, Hideo Kigoshi, Kenji Niiyama, Haruki Niwa, and Kiyoyuki Yamada:
    Stereocontrolled Total Synthesis of (+)-Tutin, a Toxic Sesquiterpene of Picrotoxane-Type,
    Tetrahedron Lett., 25 (35), 3873-3874 (1984).
  6. Iwao Hirono, Kiyoyuki Yamada, Haruki Niwa, Yoshikazu Shizuri, Makoto Ojika, Shigetoshi Hosaka, Taketo Yamaji, Kazumasa Wakamatsu, Hideo Kigoshi, Kenji Niiyama, and Youichi Uosaki:
    Separation of Carcinogenic Fraction of Bracken Fern,
    Cancer Lett., 21, 239-246 (1984).
  7. Iwao Hirono, Y. Kono, K. Takahashi, Kiyoyuki Yamada, Haruki Niwa, Makoto Ojika, Hideo Kigoshi, Kenji Niiyama, and Y. Uosaki:
    Reproduction of Acute Bracken Poisoning in a Calf with Ptaquiloside, a Bracken Constituent,
    Veterinary Record, 115, 375-378 (1984).
  8. Iwao Hirono, Shigetoshi Aiso, Taketo Yamaji, Hideki Mori, Kiyoyuki Yamada, Haruki Niwa, Makoto Ojika, Kazumasa Wakamatsu, Hideo Kigoshi, Kenji Niiyama, and Youichi Uosaki:
    Carcinogenicity in Rats of Ptaquiloside Isolated from Bracken,
    Gann, 75 (10), 833-836 (1984).
  9. Hideki Mori, Shigeyuki Sugie, Iwao Hirono, Kiyoyuki Yamada, Haruki Niwa, Makoto Ojika, Kazumasa Wakamatsu, and Hideo Kigoshi:
    Genotoxicity of Ptaquiloside, a Bracken Carcinogen, in the Hepatocyte Primary Culture/DNA-Repair Test,
    Mutation Res., 143, 75-78 (1985); Corrigenda 144, 287 (1985).
  10. Makoto Ojika, Hideo Kigoshi, Hiroki Kuyama, Haruki Niwa, and Kiyoyuki Yamada:
    Studies on Pteridium aquilinum var. latiusculum, IV. Isolation of Three p-Hydroxystyrene Glycosides and an Efficient Method for the Isolation of Ptaquiloside, an Unstable Bracken Carcinogen,
    J. Nat. Prod., 48 (4), 634-637 (1985).
  11. Hideo Kigoshi, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    Four New C15 Acetylenic Polyenes of Biogenetic Significance from the Red Alga Laurencia okamurai: Structures and Synthesis,
    Tetrahedron, 42 (14), 3781-3787 (1986).
  12. Hideo Kigoshi, Makoto Ojika, Yoshikazu Shizuri, Haruki Niwa, and Kiyoyuki Yamada:
    Isolation of (10R,11R)-(+)-Squalene-10,11-epoxide from the Red Alga Laurencia okamurai and Its Enantioselective Synthesis,
    Tetrahedron, 42 (14), 3789-3792 (1986).
  13. Kazumasa Wakamatsu, Hideo Kigoshi, Kenji Niiyama, Haruki Niwa, and Kiyoyuki Yamada:
    Stereocontrolled Total Synthesis of (+)-Tutin and (+)-Asteromurin A, Toxic Picrotoxane Sesquiterpenes,
    Tetrahedron, 42 (20), 5551-5558 (1986).
  14. Hideo Kigoshi, Yoshifumi Imamura, Haruki Niwa, and Kiyoyuki Yamada:
    Total Synthesis of Ptaquilosin: The Aglycon of Ptaquiloside, a Potent Bracken Carcinogen,
    J. Am. Chem. Soc., 111 (6), 2302-2303 (1989).
  15. Hideo Kigoshi, Akihiko Sawada, Yoshisuke Nakayama, Haruki Niwa, and Kiyoyuki Yamada:
    Stereocontrolled Total Synthesis of (±)-Ptaquilosin, the Aglycone of Ptaquiloside, a Bracken Carcinogen,
    Tetrahedron Lett., 30 (15), 1983-1986 (1989).
  16. Hideo Kigoshi, Akihiko Sawada, Haruki Niwa, and Kiyoyuki Yamada:
    Synthesis of a Functionalized Carbocyclic Skeleton of Ptaquilosin, the Aglycone of a Bracken Carcinogen Ptaquiloside Based on an Intramolecular Diels-Alder Reaction,
    Bull. Chem. Soc. Jpn., 62 (5), 1639-1642 (1989).
  17. Hideo Kigoshi, Akihiko Sawada, Yoshifumi Imamura, Haruki Niwa, and Kiyoyuki Yamada:
    Ptaquilosin, the Aglycone of a Bracken Carcinogen Ptaquiloside: Chemical Derivation from Ptaquiloside and the Reactivity,
    Tetrahedron, 45 (9), 2551-2556 (1989).
  18. Hideo Kigoshi, Yoshifumi Imamura, Kohji Yoshikawa, and Kiyoyuki Yamada:
    Three New Cytotoxic Alkaloids, Aplaminone, Neoaplaminone and Neoaplaminone Sulfate from the Marine Mollusc Aplysia kurodai,
    Tetrahedron Lett., 31 (34), 4911-4914 (1990).
  19. Hideo Kigoshi, Haruki Niwa, Kiyoyuki Yamada, Thomas J. Stout, and Jon Clardy:
    The Three-Dimensional Structure of Neohalicholactone, an Unusual Fatty Acid Metabolite from the Marine Sponge Halichondria okadai Kadota,
    Tetrahedron Lett., 32 (22), 2427-2428 (1991).
  20. Hideo Kigoshi, Yoshifumi Imamura, Kohji Yoshikawa, Haruki Niwa, and Kiyoyuki Yamada:
    Factors That Cause Contrasteric Alkylation of a Cyclopentane-1,2-dicarboxylic Acid Monoester,
    Tetrahedron Lett., 32 (35), 4541-4544 (1991).
  21. Hideo Kigoshi, Yoshifumi Imamura, Akihiko Sawada, Haruki Niwa, and Kiyoyuki Yamada:
    Novel Transformation of Formyl Groups into Hydroxyl Groups Utilizing Deformylative Autoxidation of Aldehydes,
    Bull. Chem. Soc. Jpn., 64 (12), 3735-3737 (1991).
  22. E. J. Corey and Hideo Kigoshi:
    A Route for the Enantioselective Total Synthesis of Antheridic Acid, the Antheridium-Inducing Factor from Anemia phyllitidis,
    Tetrahedron Lett., 32 (38), 5025-5028 (1991).
  23. Hideo Kigoshi, Yuichi Adachi, Kohji Yoshikawa, and Kiyoyuki Yamada:
    Absolute Stereochemistry of Aplaminone and Neoaplaminone, Cytotoxic Bromodopamines from a Marine Mollusc: Enantioselective Synthesis of Debromoneoaplaminone,
    Tetrahedron Lett., 33 (29), 4195-4198 (1992).
  24. Makoto Ojika, Hideo Kigoshi, Kohji Yoshikawa, Yoshisuke Nakayama, and Kiyoyuki Yamada:
    A New Bromo Diterpene, epi-Aplysin-20, and ent-Isoconcinndiol from the Marine Mollusc Aplysia kurodai,
    Bull. Chem. Soc. Jpn., 65 (8), 2300-2302 (1992).
  25. Hideo Kigoshi, Hideyuki Tanaka, Junichi Hirokawa, Kazuhiro Mizuta, and Kiyoyuki Yamada:
    Synthesis of Analogues of a Bracken Ultimate Carcinogen and Their DNA Cleaving Activities,
    Tetrahedron Lett., 33 (44), 6647-6650 (1992).
  26. Iwao Hirono, Mitsuya Ito, Shigeru Yagyu, Masanobu Higa, Kazumasa Wakamatsu, Teruaki Kishikawa, Osamu Nishikawa, Kiyoyuki Yamada, Makoto Ojika, and Hideo Kigoshi:
    Reproduction of Progressive Retinal Degeneration (Bright Blindness) in Sheep by Administration of Ptaquiloside Contained in Bracken,
    J. Vet. Med. Sci., 55 (6), 979-983 (1993).
  27. Hideo Kigoshi, Yoshifumi Imamura, Kazuhiro Mizuta, Haruki Niwa, and Kiyoyuki Yamada:
    Total Synthesis of Natural (-)-Ptaquilosin, the Aglycon of a Potent Bracken Carcinogen Ptaquiloside, and the (+)-Enantiomer and Their DNA Cleaving Activities,
    J. Am. Chem. Soc., 115 (8), 3056-3065 (1993).
  28. Makoto Ojika, Hideo Kigoshi, Takeshi Ishigaki, and Kiyoyuki Yamada:
    Further Studies on Aplyronine A, an Antitumor Substance Isolated from the Sea Hare Aplysia kurodai,
    Tetrahedron Lett., 34 (52), 8501-8504 (1993).
  29. Makoto Ojika, Hideo Kigoshi, Takeshi Ishigaki, Masanori Nisiwaki, Itaru Tsukada, Kazuhiro Mizuta, and Kiyoyuki Yamada:
    Studies on the Stereochemistry of Aplyronine A: Determination of the Stereochemistry of the C21-C34 Fragment,
    Tetrahedron Lett., 34 (52), 8505-8508 (1993).
  30. Tatsushi Kushida, Motonari Uesugi, Yukio Sugiura, Hideo Kigoshi, Hideyuki Tanaka, Junichi Hirokawa, Makoto Ojika, and Kiyoyuki Yamada:
    DNA Damage by Ptaquiloside, a Potent Carcinogen: Detection of Selective Strand Breaks and Identification of DNA Cleavage Products,
    J. Am. Chem. Soc., 116 (2), 479-486 (1994).
  31. Hideo Kigoshi, Makoto Ojika, Kiyotake Suenaga, Tsuyoshi Mutou, Junko Hirano, Akira Sakakura, Takeshi Ogawa, Masanori Nisiwaki, and Kiyoyuki Yamada:
    Synthetic Studies on Aplyronine A a Potent Antitumor Substance of Marine Origin: Stereocontrolled Synthesis of the C21-C34 Segment,
    Tetrahedron Lett., 35 (8), 1247-1250 (1994).
  32. Makoto Ojika, Hideo Kigoshi, Takeshi Ishigaki, Itaru Tsukada, Takaya Tuboi, Takeshi Ogawa, and Kiyoyuki Yamada:
    Absolute Stereochemistry of Aplyronine A, a Potent Antitumor Substance of Marine Origin,
    J. Am. Chem. Soc., 116 (16), 7441-7442 (1994).
  33. Hideo Kigoshi, Makoto Ojika, Takeshi Ishigaki, Kiyotake Suenaga, Tsuyoshi Mutou, Akira Sakakura, Takeshi Ogawa, and Kiyoyuki Yamada:
    Total Synthesis of Aplyronine A, a Potent Antitumor Substance of Marine Origin,
    J. Am. Chem. Soc., 116 (16), 7443-7444 (1994).
  34. Hiroyuki Ishiwata, Hiroki Sone, Hideo Kigoshi, and Kiyoyuki Yamada:
    Total Synthesis of Doliculide, a Potent Cytotoxic Cyclodepsipeptide from the Japanese Sea Hare Dolabella auricularia,
    J. Org. Chem., 59 (17), 4712-4713 (1994).
  35. Hiroyuki Ishiwata, Hiroki Sone, Hideo Kigoshi, and Kiyoyuki Yamada:
    Enantioselective Total Synthesis of Doliculide, a Potent Cytotoxic Cyclodepsipeptide of Marine Origin and Structure-Cytotoxicity Relationships of Synthetic Doliculide Congeners,
    Tetrahedron, 50 (45), 12853-12882 (1994).
  36. Kiyotake Suenaga, Takeshi Ishigaki, Akira Sakakura, Hideo Kigoshi, and Kiyoyuki Yamada:
    Absolute Stereochemistry and Synthesis of Aplyronines B and C, the Congeners of Aplyronine A, a Potent Antitumor Substance of Marine Origin,
    Tetrahedron Lett., 36 (28), 5053-5056 (1995).
  37. Hideo Kigoshi, Misako Niwa, Hidekazu Ohashi, Hideyuki Tanaka, Junichi Hirokawa, Hiroyuki Ishiwata, and Kiyoyuki Yamada:
    Synthesis of Bracken Ultimate Carcinogen Analogues Possessing a DNA Binding Moiety and Their DNA Cleaving Activities,
    Tetrahedron Lett., 36 (30), 5349-5352 (1995).
  38. Kiyotake Suenaga, Hideo Kigoshi, and Kiyoyuki Yamada:
    Auripyrones A and B, Cytotoxic Polypropionates from the Sea Hare Dolabella auricularia: Isolation and Structures,
    Tetrahedron Lett., 37 (29), 5151-5154 (1996).
  39. Hideo Kigoshi, Kiyotake Suenaga, Tsuyoshi Mutou, Takeshi Ishigaki, Toshiyuki Atsumi, Hiroyuki Ishiwata, Akira Sakakura, Takeshi Ogawa, Makoto Ojika, and Kiyoyuki Yamada:
    Aplyronine A, a Potent Antitumor Substance of Marine Origin, Aplyronines B and C, and Artificial Analogues: Total Synthesis and Structure-Cytotoxicity Relationships,
    J. Org. Chem., 61 (16), 5326-5351 (1996).
  40. Kiyotake Suenaga, Tsuyoshi Mutou, Takunobu Shibata, Takashi Itoh, Hideo Kigoshi, and Kiyoyuki Yamada:
    Isolation and Stereostructure of Aurilide, a Novel Cyclodepsipeptide from the Japanese Sea Hare Dolabella auricularia,
    Tetrahedron Lett., 37 (37), 6771-6774 (1996).
  41. Shin-ya Saito, Shugo Watabe, Hiroshi Ozaki, Hideo Kigoshi, Kiyoyuki Yamada, Nobuhiro Fusetani, and Hideaki Karaki:
    Novel Actin Depolymerizing Macrolide Aplyronine A,
    J. Biochem., 120 (3), 552-555 (1996).
  42. Tsuyoshi Mutou, Takashi Kondo, Takunobu Shibata, Makoto Ojika, Hideo Kigoshi, and Kiyoyuki Yamada:
    Synthesis of Dolastatin G and Nordolastatin G, Cytotoxic 35-Membered Cyclodepsipeptides of Marine Origin,
    Tetrahedron Lett., 37 (40), 7299-7302 (1996).
  43. Hiroki Sone, Hideo Kigoshi, and Kiyoyuki Yamada:
    Aurisides A and B, Cytotoxic Macrolide Glycosides from the Japanese Sea Hare Dolabella auricularia,
    J. Org. Chem., 61 (25), 8956-8960 (1996).
  44. Kiyotake Suenaga, Noriyuki Kamei, Youko Okugawa, Masaki Takagi, Atsushi Akao, Hideo Kigoshi, and Kiyoyuki Yamada:
    Cytotoxicity and Actin Depolymerizing Activity of Aplyronine A, a Potent Antitumor Macrolide of Marine Origin, and the Natural and Artificial Analogs,
    Bioorg. Med. Chem. Lett., 7 (3), 269-274 (1997).
  45. Tsuyoshi Mutou, Kiyotake Suenaga, Tatsuya Fujita, Takashi Itoh, Noboru Takada, Kozue Hayamizu, Hideo Kigoshi, and Kiyoyuki Yamada:
    Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin,
    Synlett, (2), 199-201 (1997).
  46. Kiyotake Suenaga, Tomohiro Nagoya, Takunobu Shibata, Hideo Kigoshi, and Kiyoyuki Yamada:
    Dolabelides C and D, Cytotoxic Macrolides Isolated from the Sea Hare Dolabella auricularia,
    J. Natl. Prod., 60 (2), 155-157 (1997).
  47. Hideo Kigoshi, Yuusi Kitamura, Tatsuya Fujita, Hidekazu Ohashi, Toshiyuki Atsumi, Junko Takagi, Tsuyoshi Mutou, Kiyoyuki Yamada, Tetsuya Kusakabe, Daisuke Sasaki, and Yukio Sugiura:
    A New Synthetic Analogue of the Bracken Ultimate Carcinogen: Elevation of Stability and Alteration of DNA Alkylation Site Selectivity,
    Tetrahedron Lett., 38 (18), 3235-3238 (1997).
  48. Hiroki Sone, Hideo Kigoshi, and Kiyoyuki Yamada:
    Isolation and Stereostructure of Dolastatin I, a Cytotoxic Cyclic Hexapeptide from the Japanese Sea Hare Dolabella auricularia,
    Tetrahedron, 53 (24), 8149-8154 (1997).
  49. Hiroki Sone, Kiyotake Suenaga, Yuhki Bessho, Takashi Kondo, Hideo Kigoshi, and Kiyoyuki Yamada:
    Synthesis of the Aglycon of Aurisides A and B, Cytotoxic Macrolide Glycosides of Marine Origin,
    Chem. Lett., (1), 85-86 (1998).
  50. Kiyotake Suenaga, Noboru Takada, Takunobu Shibata, Hideo Kigoshi, and Kiyoyuki Yamada:
    Aurilol, a Cytotoxic Bromotriterpene Isolated from the Sea Hare Dolabella auricularia,
    J. Nat. Prod., 61 (4), 515-518 (1998).
  51. Hideo Kigoshi, Kengo Kanematsu, and Daisuke Uemura:
    Turbotoxins A and B, Novel Diiodotyramine Derivatives from the Japanese Gastropod Turbo marmorata,
    Tetrahedron Lett., 40 (31), 5745-5748 (1999).
  52. Hideo Kigoshi and Shiho Yamada:
    Synthesis of Dolastatin I, a Cytotoxic Cyclic Hexapeptide from the Sea Hare Dolabella auricularia,
    Tetrahedron, 55 (42), 12301-12308 (1999).
  53. Hideo Kigoshi, Yuto Suzuki, Kenta Aoki, and Daisuke Uemura:
    Synthetic Studies of Ingenol: Synthesis of in,out-Tricyclo[7.4.1.01,5]tetradecan-14-one,
    Tetrahedron Lett., 41 (20), 3927-3930 (2000).
  54. Hideo Kigoshi, Kengo Kanematsu, Kyoko Yokota, and Daisuke Uemura:
    Turbotoxins A and B, Novel Diiodotyramine Derivatives from the Japanese Gastropod Turbo marmorata,
    Tetrahedron, 56 (46), 9063-9070 (2000).
  55. Hideo Kigoshi, Takao Ichino, Kaoru Yamada, Yasuharu Ijuin, Solange Fumi Makita, and Daisuke Uemura:
    Stereostructure and Bioactivities of Jolkinolide D,
    Chem. Lett., 2001 (6), 518-519 (2001).
  56. Masaki Kita, Hideo Kigoshi, and Daisuke Uemura:
    Isolation and Structure of Korolkoside, a Bis-Iridoid Glucoside from Lonicera korolkovii,
    J. Nat. Prod., 64 (8), 1090-1092 (2001).
  57. Hideo Kigoshi, Takashi Itoh, Takafumi Ogawa, Kenya Ochi, Mayuko Okada, Kiyotake Suenaga, and Kiyoyuki Yamada:
    Auriculol, a Cytotoxic Oxygenated Squalene from the Japanese Sea Hare Dolabella auricularia: Isolation, Stereostructure, and Synthesis,
    Tetrahedron Lett., 42 (42), 7461-7464 (2001).
  58. Hideo Kigoshi, Norimitsu Hayashi, and Daisuke Uemura:
    Stereoselective Synthesis of Pinnamine, an Alkaloidal Marine Toxin from Pinna muricata,
    Tetrahedron Lett., 42 (42), 7469-7471 (2001).
  59. Hideo Kigoshi, Kiyotake Suenaga, Masaki Takagi, Atsushi Akao, Kengo Kanematsu, Noriyuki Kamei, Youko Okugawa, and Kiyoyuki Yamada:
    Cytotoxicity and Actin-Depolymerizing Activity of Aplyronine A, a Potent Antitumor Macrolide of Marine Origin, and Its Analogs,
    Tetrahedron, 58 (6), 1075-1102 (2002).
  60. Akira Sakakura, Yui Takayanagi, and Hideo Kigoshi:
    Jolkinolide D Pharmacophore: Synthesis and Reaction with Amino Acids, Nucleosides, and DNA,
    Tetrahedron Lett., 43 (34), 6055-6058 (2002).
  61. Hideo Kigoshi, Masaki Kita, Seiji Ogawa, Masahiro Itoh, and Daisuke Uemura:
    Enantioselective Synthesis of 15-epi-Haterumalide NA Methyl Ester and Revised Structure of Haterumalide NA,
    Org. Lett., 5 (6), 957-960 (2003).
  62. Hideo Kigoshi, Takao Ichino, Noboru Takada, Kiyotake Suenaga, Akihiro Yamada, Kaoru Yamada, and Daisuke Uemura:
    Isolation of Tribromoacetamide from an Okinawan Alga and Biological Activities of Its Analogs,
    Chem. Lett., 33 (2), 98-99 (2004).
  63. Hiroki Shimogawa, Youngjoo Kwon, Qian Mao, Yoshinori Kawazoe, Yongmun Choi, Shinichi Asada, Hideo Kigoshi, and Motonari Uesugi:
    A Wrench-shaped Synthetic Molecule That Modulates a Transcription Factor-Coactivator Interaction,
    J. Am. Chem. Soc., 126 (11), 3461-3471 (2004).
  64. Kiyotake Suenaga, Saori Miya, Takeshi Kuroda, Tomohisa Handa, Kengo Kanematsu, Akira Sakakura, and Hideo Kigoshi:
    Synthesis and Actin-depolymerizing Activity of Mycalolide Analogs,
    Tetrahedron Lett., 45 (28), 5383-5386 (2004).
  65. Akira Sakakura, Yui Takayanagi, Hiroki Shimogawa, and Hideo Kigoshi:
    Jolkinolide D Pharmacophore: Synthesis and Reaction with Amino Acids, Nucleosides, and DNA,
    Tetrahedron, 60 (33), 7067-7075 (2004).
  66. Kiyotake Suenaga, Yui Takayanagi, Masashi Yamaura, and Hideo Kigoshi:
    Total Synthesis of (-)-ent-Jolkinolide D,
    Chem. Lett., 33 (7), 918-919 (2004).
  67. Toshiaki Teruya, Hiroki Shimogawa, Kiyotake Suenaga, and Hideo Kigoshi:
    Biselides A and B, Novel Macrolides from the Okinawan Ascidian Didemnidae sp.,
    Chem. Lett., 33 (9), 1184-1185 (2004).
  68. Kiyotake Suenaga, Tsuyoshi Mutou, Takunobu Shibata, Takashi Itoh, Tatsuya Fujita, Noboru Takada, Kozue Hayamizu, Masaki Takagi, Taiji Irifune, Hideo Kigoshi, and Kiyoyuki Yamada:
    Aurilide, a Cytotoxic Depsipeptide from the Sea Hare Dolabella auricularia: Isolation, Structure Determination, Synthesis, and Biological Activity,
    Tetrahedron, 60 (38), 8509-8527 (2004).
  69. Keiko Kobayashi, Hiroki Shimogawa, Akira Sakakura, Toshiaki Teruya, Kiyotake Suenaga, and Hideo Kigoshi.
    Spongiacysteine, a Novel Cysteine Derivative from the Marine Sponge Spongia sp.,
    Chem. Lett., 33 (10), 1262 -1263 (2004).
  70. Kazushi Watanabe, Yuto Suzuki, Kenta Aoki, Akira Sakakura, Kiyotake Suenaga, and Hideo Kigoshi.
    Formal Synthesis of Optically Active Ingenol via Ring-Closing Olefin Metathesis,
    J. Org. Chem., 69 (23), 7802-7808 (2004).
  71. Toshiaki Teruya, Keiko Kobayashi, Kiyotake Suenaga, and Hideo Kigoshi:
    Phormidinines A and B, Novel 2-Alkylpyridine Alkaloids from the Cyanobacterium Phormidium sp.,
    Tetrahedron Lett., 46 (23), 4001-4003 (2005).
  72. Toshiaki Teruya, Kiyotake Suenaga, Sakiko Maruyama,Mineko Kurotakiand, and Hideo Kigoshi:
    Biselides A-E: Novel Polyketides from the Okinawan Ascidian Didemnidae sp.,
    Tetrahedron, 61 (27), 6561-6567 (2005).
  73. Hiroki Shimogawa, Toshiaki Teruya, Kiyotake Suenaga, and Hideo Kigoshi:
    Isolation of Two 13-epi-Neoverrucosane-Type Diterpenoids from a Marine Sponge Axinyssa tethyoides,
    Bull. Chem. Soc. Jpn., 78 (7), 1345-1347 (2005).
  74. Shinya Nomoto and Hideo Kigoshi:
    GC/MS Analysis of Maleimides in Present Sediments and of Those Produced by Chromic Acid Oxidation of Neogene Sedimentary Rocks,
    Researches of Organic Geochemistry, 20, 31-37 (2005).
  75. Ichiro Hayakawa, Toshiaki Teruya, and Hideo Kigoshi:
    Revised Structure of Zamamistatin,
    Tetrahedron Lett., 47 (1), 155-158 (2006).
  76. Hiroki Shimogawa, Satomi Kuribayashi, Toshiaki Teruya, Kiyotake Suenaga and Hideo Kigoshi:
    Cinachyramine, the Novel Alkaloid Possessing a Hydrazone and Two Aminals from Cinachyrella sp.,
    Tetrahedron Lett., 47 (9), 1409-1411 (2006).
  77. Toshiaki Teruya, Keiko Kobayashi, Kiyotake Suenaga, and Hideo Kigoshi:
    Cyclohaliclonamines A-E: Dimeric, Trimeric, Tetrameric, Pentameric, and Hexameric 3-Alkyl Pyridinium Alkaloids from a Marine Sponge Haliclona sp.,
    J. Nat. Prod., 69 (1), 135-139 (2006).
  78. Kunio Hirata, Shin Muraoka, Kiyotake Suenaga, Takeshi Kuroda, Kenichi Kato, Hiroshi Tanaka, Masaki Yamamoto, Masaki Takata, Kiyoyuki Yamada, and Hideo Kigoshi:
    Structure Basis for Antitumor Effect of Aplyronine A,
    J. Mol. Biol., 356 (4), 945-954 (2006).
    紹介記事(61番をご覧ください)
  79. Takeshi Kuroda, Kiyotake Suenaga, Akira Sakakura, Tomohisa Handa, Kazuhito Okamoto, and Hideo Kigoshi:
    Study of the Interaction between Actin and Antitumor Substance Aplyronine A with a Novel Fluorescent Photoaffinity Probe,
    Bioconjugate Chem., 17 (2), 524-529 (2006).
  80. Keiko Kobayashi, Toshiaki Teruya, Kiyotake Suenaga, Yoko Matsui, Hideki Masuda, and Hideo Kigoshi:
    Isotheasaponins B1-B3 from Camellia sinensis var. sinensis Tea Leaves,
    Phytochemistry, 67 (13), 1385-1389 (2006).
  81. Kiyotake Suenaga, Hiroshi Hoshino, Takanori Yoshii, Kazunori Mori, Hiroki Sone, Yuhki Bessho, Akira Sakakura, Ichiro Hayakawa, Kiyoyuki Yamada and Hideo Kigoshi:
    Enantioselective Synthesis of Aurisides A and B, Cytotoxic Macrolide Glycosides of Marine Origin,
    Tetrahedron, 62 (33), 7687-7698 (2006).
  82. Kiyotake Suenaga, Tomoyuki Kimura, Takeshi Kuroda, Keita Matsui, Saori Miya, Satomi Kuribayashi, Akira Sakakura, and Hideo Kigoshi:
    Synthesis and Biological Activity of Mycalolide Analogs,
    Tetrahedron, 62 (35), 8278-8290 (2006).
  83. Makoto Ojika, Hideo Kigoshi, Yoshifumi Yoshida, Takeshi Ishigaki, Masanori Nisiwaki, Itaru Tsukada, Masayuki Arakawa, Hisao Ekimoto, and Kiyoyuki Yamada:
    Aplyronine A, a Potent Antitumor Macrolide of Marine Origin, and the Congeners Aplyronines B and C: Isolation, Structures, and Bioactivities,
    Tetrahedron, 63 (15), 3138-3167 (2007).
  84. Ichiro Hayakawa, Yuki Asuma, Takayuki Ohyoshi, Kenta Aoki, and Hideo Kigoshi:
    Synthetic Study on 13-Oxyingenol: Construction of the Full Carbon Framework,
    Tetrahedron Lett., 48 (35), 6221-6224 (2007).
  85. Ichiro Hayakawa, Akiyuki Ikedo, and Hideo Kigoshi:
    Synthesis of Glaziovianin A, a Potent Antitumor Isoflavone,
    Chemistry Lett., 36 (11), 1382-1383 (2007).
  86. Tomoyuki Kimura, Satomi Kuribayashi, Tetsuya Sengoku, Keita Matsui, Shoko Ueda, Ichiro Hayakawa, Kiyotake Suenaga, and Hideo Kigoshi:
    Synthetic Studies on Mycalolide B: Synthesis of the C7-C35 Fragment,
    Chemistry Lett., 36 (12), 1490-1491 (2007).
  87. Takahiro Miyake, Hideo Kigoshi, and Hiroyuki Akita:
    Chemoenzymatic Synthesis of (+)-Totarol, (+)-Podototarin, (+)-Sempervirol, and (+)-Jolkinolides E and D,
    Tetrahedron: Asymmetry, 18 (24), 2915-2922 (2007).
  88. Takeshi Kuroda and Hideo Kigoshi:
    Aplaminal: A Novel Cytotoxic Aminal Isolated from the Sea Hare Aplysia kurodai,
    Org. Lett., 10 (3), 489-491 (2008).
  89. Ichiro Hayakawa, Mitsuru Ueda, Masashi Yamaura, Yoichi Ikeda, Yuta Suzuki, Kensaku Yoshizato, and Hideo Kigoshi:
    Second-Generation Total Synthesis of Haterumalide NA Using B-Alkyl Suzuki-Miyaura Coupling,
    Org. Lett., 10 (9), 1859-1862 (2008).
  90. Shinya Nomoto, Mitsuru Satou, Takahiro Yoshida, Hajime Mita, Gen Kumagai, Kouichi Nomoto, Hideo Kigoshi, and Yuichiro Kashiyama:
    The First Experimental Demonstration of Benzoporphyrin Formation from Sedimentary Porphyrins,
    Chemistry Lett., 37 (5), 490-491 (2008).
  91. Kiyotake Suenaga, Shuri Kajiwara, Satomi Kuribayashi, Tomohisa Handa, and Hideo Kigoshi:
    Synthesis and Cytotoxicity of Aurilide Analogs,
    Bioorg. Med. Chem. Lett., 18 (14), 3902-3905 (2008).
  92. Ichiro Hayakawa, Hidekazu Watanabe, and Hideo Kigoshi:
    Synthesis of Ustalic Acid, an Inhibitor of Na+,K+-ATPase,
    Tetrahedron, 64 (25), 5873-5877 (2008).
  93. Masaki Kita, Yuta Tsunematsu, Ichiro Hayakawa, and Hideo Kigoshi:
    Structure of Zamamistatin - a Correction,
    Tetrahedron Lett., 49 (37), 5383-5384 (2008).
  94. Tetsuya Sengoku, Takuma Takemura, Emi Fukasawa, Ichiro Hayakawa, and Hideo Kigoshi:
    Aldol-type Reaction of a 4-Pyrone: a Straightforward Approach to 4-Pyrone-containing Natural Products,
    Tetrahedron Lett., 50 (3), 325-328 (2009).
  95. Kazuhiro Kitamura, Toshiaki Teruya, Takeshi Kuroda, Hideo Kigoshi, and Kiyotake Suenaga:
    Synthesis of Actin-depolymerizing Compounds,
    Bioorg. Med. Chem. Lett., 19 (7), 1896-1898 (2009).
  96. Takashi Yoshizumi, Akio Ohno, Tomohiro Tsujita, Hirobumi Takahashi, Osamu Okamoto, Ichiro Hayakawa, and Hideo Kigoshi:
    Practical Syntheses of Optically Pure Key Intermediates of Opioid Receptor-like 1 (ORL1) Antagonists,
    Synthesis, 2009 (7), 1153-1163.
  97. Mitsuru Ueda, Masashi Yamaura, Yoichi Ikeda, Yuta Suzuki, Kensaku Yoshizato, Ichiro Hayakawa, and Hideo Kigoshi:
    Total Synthesis and Cytotoxicity of Haterumalides NA and B and their Artificial Analogs,
    J. Org. Chem., 74 (9), 3370-3377 (2009).
  98. Dongju Jung, Hiroki Shimogawa, Youngjoo Kwon, Qian Mao, Shin-ichi Sato, Shinji Kamisuki, Hideo Kigoshi, and Motonari Uesugi:
    Wrenchnolol Derivative Optimized for Gene Activation in Cells,
    J. Am. Chem. Soc., 131 (13), 4774-4782 (2009).
  99. Yoko Matsui, Keiko Kobayashi, Hideki Masuda, Hideo Kigoshi, Makoto Akao, Hidetoshi Sakurai, and Hitomi Kumagai:
    Quantitative Analysis of Saponins in a Tea-leaf Extract and Their Antihypercholesterolemic Activity,
    Biosci. Biotechnol. Biochem., 73 (7), 1513-1519 (2009).
  100. Masaki Kita, David StC. Black, Osamu Ohno, Kaoru Yamada, Hideo Kigoshi, and Daisuke Uemura:
    Duck-Billed Platypus Venom Peptides Induce Ca2+ Influx in Neuroblastoma Cells,
    J. Am. Chem. Soc., 131 (50), 18038-18039 (2009).
  101. Ichiro Hayakawa, Takuma Takemura, Emi Fukasawa, Yuta Ebihara, Natsuki Sato, Takayasu Nakamura, Kiyotake Suenaga, and Hideo Kigoshi:
    Total Synthesis of Auripyrones A and B and Determination of the Absolute Configuration of Auripyrone B,
    Angew. Chem. Int. Ed., 49 (13), 2401-2405 (2010); Angew. Chem., 122 (13), 2451-2455 (2010).
  102. Akiyuki Ikedo, Ichiro Hayakawa, Takeo Usui, Sayaka Kazami, Hiroyuki Osada, and Hideo Kigoshi:
    Structure-activity Relationship Study of Glaziovianin A against Cell Cycle Progression and Spindle Formation of HeLa S3 Cells,
    Bioorg. Med. Chem. Lett., 20 (18), 5402-5404 (2010).
  103. Masaki Kita, Hidekazu Watanabe, Tomoya Ishitsuka, Yuzo Mogi, and Hideo Kigoshi:
    Synthetic Studies of Mycalolide B, an Actin-depolymerizing Marine Macrolide: Construction of the Tris-oxazole Macrolactone Using Ring-closing Metathesis,
    Tetrahedron Lett., 51 (37), 4882-4885 (2010).
  104. Shin-ichi Sato, Asako Murata, Tsubasa Orihara, Takashi Shirakawa, Kiyotake Suenaga, Hideo Kigoshi, and Motonari Uesugi:
    Marine Natural Product Aurilide Activates the OPA1-Mediated Apoptosis by Binding to Prohibitin,
    Chem. Biol., 18 (1), 131-139 (2011).
  105. Ichiro Hayakawa, Yamato Miyazawa, Takayuki Ohyoshi, Yuki Asuma, Kenta Aoki, and Hideo Kigoshi:
    Synthetic Studies toward Optically Active 13-Oxyingenol via Asymmetric Cyclopropanation,
    Synthesis, (5), 769-777 (2011).
  106. Kenichi Kobayashi, Yusuke Fujii, Ichiro Hayakawa, and Hideo Kigoshi:
    Toward the Second Generation Synthesis of Aplyronine A: Stereocontrolled Assembly of the C1-C19 Segment by Using an Asymmetric Nozaki-Hiyama-Kishi Coupling,
    Org. Lett., 13 (5), 900-903 (2011).
  107. Takayuki Ohyoshi, Yamato Miyazawa, Kenta Aoki, Satomi Ohmura, Yuki Asuma, Ichiro Hayakawa, and Hideo Kigoshi:
    Synthetic Studies Toward 13-Oxyingenol: Construction of the Fully Substituted Tetracyclic Compound,
    Org. Lett., 13 (9), 2160-2163 (2011).
  108. Masaki Kita, Yuichiro Hirayama, Miyuki Sugiyama, and Hideo Kigoshi:
    Development of Highly Cytotoxic and Actin-Depolymerizing Biotin Derivatives of Aplyronine A,
    Angew. Chem. Int. Ed., 50 (42), 9871-9874 (2011).
  109. Makoto Ojika, Hideo Kigoshi, Kiyotake Suenaga, Yoshifumi Imamura, Kohji Yoshikawa, Takeshi Ishigaki, Akira Sakakura, Tsuyoshi Mutou, and Kiyoyuki Yamada:
    Aplyronines D-H from the Sea Hare Aplysia kurodai: Isolation, Structures, and Cytotoxicity,
    Tetrahedron, 68 (4), 982-987 (2012).
  110. Kenichi Kobayashi, Yusuke Fujii, Yuichiro Hirayama, Shinichi Kobayashi, Ichiro Hayakawa, and Hideo Kigoshi:
    Design, Synthesis, and Biological Evaluations of Aplyronine A-Mycalolide B Hybrid Compound,
    Org. Lett., 14 (5), 1290-1293 (2012).
  111. Yohsuke Satoh, Dai Kawamura, Masashi Yamaura, Yoichi Ikeda, Yumi Ochiai, Ichiro Hayakawa, and Hideo Kigoshi:
    Synthetic Studies towards Biselides. Part 1: Synthesis of the Core Carbon Framework of Biselides A, B, and E Using Stille Coupling,
    Tetrahedron Lett., 53 (11), 1390-1392 (2012).
  112. Yohsuke Satoh, Takuya Yamada, Yuto Onozaki, Dai Kawamura, Ichiro Hayakawa, and Hideo Kigoshi:
    Synthetic Studies toward Biselides. Part 2: Synthesis of the Macrolactone Part of Biselides A and B Using Allylic Oxidation,
    Tetrahedron Lett., 53 (11), 1393-1396 (2012).
  113. Takayuki Ohyoshi, Shota Funakubo, Yamato Miyazawa, Keisuke Niida, Ichiro Hayakawa, and Hideo Kigoshi:
    Total Synthesis of (-)-13-Oxyingenol and its Natural Derivative,
    Angew. Chem. Int. Ed., 51 (20), 4972-4975 (2012).
  114. Takuma Takemura, Ichiro Hayakawa, Emi Fukasawa, Tetsuya Sengoku, and Hideo Kigoshi:
    Toward the synthesis of .gamma.-pyrone-containing natural products: Diastereoselective aldol-type reaction of a .gamma.-pyrone,
    Tetrahedron, 68 (32), 6477-6484 (2012).
  115. Masaki Kita, Kozo Yoneda, Yuichiro Hirayama, Kota Yamagishi, Yuki Saito, Yuka Sugiyama, Yoshihiro Miwa, Osamu Ohno, Maho Morita, Kiyotake Suenaga, and Hideo Kigoshi:
    Fluorescent Aplyronine A: Intracellular Accumulation and Disassembly of Actin Cytoskeleton in Tumor Cells,
    ChemBioChem, 13 (12), 1754-1758 (2012).
  116. Ichiro Hayakawa, Takuma Takemura, Emi Fukasawa, Yuta Ebihara, Natsuki Sato, Takayasu Nakamura, Kiyotake Suenaga, and Hideo Kigoshi:
    Total synthesis and biological evaluation of auripyrones A and B,
    Bull. Chem. Soc. Jpn., 85 (10), 1077-1092 (2012).
    *BCSJ Award Article (2012)
  117. Masaki Kita, Hirotaka Oka, Akihiro Usui, Tomoya Ishitsuka, Yuzo Mogi, Hirokazu Watanabe, and Hideo Kigoshi:
    Synthesis and Biological Activities of the Tris-oxazole Macrolactone Analogs of Mycalolides,
    Tetrahedron, 68 (42), 8753-8760 (2012).
  118. Ichiro Hayakawa, Akiyuki Ikedo, Takumi Chinen, Takeo Usui, and Hideo Kigoshi:
    Design, synthesis, and biological evaluation of the analogues of glaziovianin A, a potent antitumor isoflavone,
    Bioorg. Med. Chem., 20 (19), 5745-5756 (2012).
  119. Masaki Kita, Yuichiro Hirayama, Kota Yamagishi, Kozo Yoneda, Ryosuke Fujisawa, and Hideo Kigoshi:
    Interactions of the Antitumor Macrolide Aplyronine A with Actin and Actin-related Proteins Established by Its Versatile Photoaffinity Derivatives,
    J. Am. Chem. Soc., 134 (50), 20314-20317 (2012).
  120. Osamu Ohno, Maho Morita, Kazuhiro Kitamura, Toshiaki Teruya, Kozo Yoneda, Masaki Kita, Hideo Kigoshi, and Kiyotake Suenaga:
    Apoptosis-inducing Activity of the Actin-depolymerizing Agent Aplyronine A and Its Side-chain Derivative,
    Bioorg. Med. Chem. Lett., 23 (5), 1467-1471 (2013).
  121. Takumi Chinen, Sayaka Kazami, Yoko Nagumo, Ichiro Hayakawa, Akiyuki Ikedo, Masatoshi Takagi, Akihito Yokosuka, Naoko Imamoto, Yoshihiro Mimaki, Hideo Kigoshi, Hiroyuki Osada, and Takeo Usui:
    Glaziovianin A prevents endosome maturation via inhibiting microtubule dynamics,
    ACS Chem. Biol. , 8 (5), 884-889 (2013).
  122. Masaki Kita, Baro Gise, Atsushi Kawamura, and Hideo Kigoshi:
    Stylissatin A, a cyclic peptide that inhibits nitric oxide production from the marine sponge Stylissa massa,
    Tetrahedron Lett., 54 (50), 6826-6828 (2013).
  123. Masaki Kita, Yuichiro Hirayama, Kozo Yoneda, Kota Yamagishi, Takumi Chinen, Takeo Usui, Eriko Sumiya, Motonari Uesugi, and Hideo Kigoshi:
    Inhibition of Microtubule Assembly by A Complex of Actin and Antitumor Macrolide Aplyronine A,
    J. Am. Chem. Soc., 135 (48), 18089-18095 (2013).
  124. Yuko Kato, Nobuhiro Fuchi, Yutaka Nishimura, Ayano Watanabe, Mai Yagi, Yasuhito Nakadera, Eriko Higashi, Masateru Yamada, Takumi Aoki, and Hideo Kigoshi:
    Discovery of 1-oxa-4,9-diazaspiro[5.5]undecane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase inhibitors and orally active drug candidates for treating of chronic kidney diseases,
    Bioorg. Med. Chem. Lett., 24 (2), 565-570 (2014).
  125. Ichiro Hayakawa, Shuya Shioda, Akiyuki Ikedo, and Hideo Kigoshi:
    Practical Synthesis of Glaziovianin A, a Cytotoxic Isoflavone, and Its O7-Propargyl Analogue,
    Bull. Chem. Soc. Jpn., 87 (4), 544-549 (2014).
  126. Tito Akindele, Baro Gise, Taiki Sunaba, Masaki Kita, and Hideo Kigoshi:
    Isolation, Synthesis and Nitric Oxide Reducing Activity of Compounds from the Marine Sponge Stylissa massa,
    Bull. Chem. Soc. Jpn., 88 (4), 600-609 (2015).
  127. Atsushi Kawamura, Masaki Kita, and Hideo Kigoshi:
    Aplysiasecosterol A: A 9,11-Secosteroid with an Unprecedented Tricyclic Gamma-diketone Structure from the Sea Hare Aplysia kurodai,
    Angew. Chem., Int. Ed., 127 (24), 7073-7076 (2015).
  128. Ichiro Hayakawa, Tomomi Nakamura, Osamu Ohno, Kiyotake Suenaga, and Hideo Kigoshi:
    Synthesis and structure-activity relationships for cytotoxicity and apoptosis-inducing activity of (+)-halichonine B,
    Org. Biomol. Chem., 13 (39), 9969-9976 (2015).
  129. Ichiro Hayakawa, Keisuke Niida, and Hideo Kigoshi:
    Construction of the [6-7-5-5] tetracyclic core of all the carbocyclic frameworks of yuzurimine-type alkaloids,
    Chem. Commun., 51 (58), 11568-11571 (2015).
  130. Masaki Kita, Hirotaka Oka, Akihiro Usui, Tomoya Ishitsuka, Yuzo Mogi, Hidekazu Watanabe, Masaki Tsunoda, and Hideo Kigoshi:
    Total Synthesis of Mycalolides A and B through Olefin Metathesis,
    Angew. Chem., Int. Ed., 54 (47), 14174-14178 (2015).
  131. Kozo Yoneda, Yaping Hu, Masaki Kita, and Hideo Kigoshi:
    6-Amidopyrene as a label-assisted laser desorption/ionization (LA-LDI) enhancing tag: development of photoaffinity pyrene derivative,
    Sci. Rep., 5, 17853 (2015). 8 pages
  132. Takumi Chinen, Peng Liu, Shuya Shioda, Judith Pagel, Berati Cerikan, Tien-Chen Lin, Oliver Gruss, Yoshiki Hayashi, Haruka Takeno, Tomohiro Shima, Yasushi Okada, Ichiro Hayakawa, Yoshio Hayashi, Hideo Kigoshi, Takeo Usui, and Elmar Schiebel:
    The .gamma.-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle,
    Nat. Commun., 6, 8722 (2015). 11 pages
  133. Yuichiro Hirayama, Peter L. Katavic, Andrew M. White, Gregory K. Pierens, Lynette K. Lambert, Anne E. Winters, Hideo Kigoshi, Masaki Kita, and Mary J. Garson:
    New Cytotoxic Norditerpenes from the Australian Nudibranchs Goniobranchus splendidus and Goniobranchus daphne,
    Aust. J. Chem., 69 (2), 136-144 (2016).
  134. Seiji Ogawa, Toshihide Watanabe, Isamu Sugimoto, Kazumi Moriyuki, Yoshikazu Goto, Shinsaku Yamane, Akio Watanabe, Kazuma Tsuboi, Atsushi Kinoshita, Hideo Kigoshi, Kousuke Tani, and Toru Maruyama:
    Discovery of G Protein-Biased EP2 Receptor Agonists,
    ACS Med. Chem. Lett., 7 (3), 306-311 (2016).
  135. Masaki Kita, Atsushi Kawamura, and Hideo Kigoshi:
    Aplysiasecosterols B and C: Two New 9,11-Secosteroids with a cis-Fused 1,4-Quinone Structure From the Sea Hare Aplysia kurodai,
    Tetrahedron Lett., 57 (8), 858-860 (2016).
  136. Yuichiro Hirayama, Kota Yamagishi, Tomohiro Suzuki, Hirokazu Kawagishi, Masaki Kita, and Hideo Kigoshi:
    Analysis of the Aplyronine A-induced Protein-Protein Interaction Between Actin and Tubulin by Surface Plasmon Resonance,
    Bioorg. Med. Chem., 24 (12), 2809-2814 (2016).
  137. Kozo Yoneda, Yaping Hu, Rei Watanabe, Masaki Kita, and Hideo Kigoshi:
    Binding Position Analysis of Target Proteins with the Use of Amidopyrene Probes as LA-LDI Enhancing Tags,
    Org. Biomol. Chem., 14 (36), 8564-8569 (2016).
  138. Ichiro Hayakawa, Shuya Shioda, Takumi Chinen, Taisei Hatanaka, Haruna Ebisu, Akira Sakakura, Takeo Usui, and Hideo Kigoshi. 2016.
    Discovery of O(6)-Benzyl Glaziovianin A, a Potent Cytotoxic Substance and a Potent Inhibitor of .alfa.,beta.-Tubulin Polymerization,
    Bioorg. Med. Chem., 24 (21), 5639-5645 (2016).
  139. Takayuki Ohyoshi, Yuki Tamura, Ichiro Hayakawa, Go Hirai, Yamato Miyazawa, Shota Funakubo, Mikiko Sodeoka, and Hideo Kigoshi:
    Total Synthesis of Natural Derivatives and Artificial Analogs of 13-Oxyingenol and Their Biological Evaluation,
    Org. Biomol. Chem., 14 (48), 11426-11437 (2016).
  140. Ichiro Hayakawa, Keita Saito, Sachiko Matsumoto, Shinichi Kobayashi, Ayaka Taniguchi, Kenichi Kobayashi, Yusuke Fujii, Takahiro Kaneko, and Hideo Kigoshi:
    Second-Generation Total Synthesis of Aplyronine A Featuring Ni/Cr-Mediated Coupling Reactions,
    Org. Biomol. Chem., 15 (1), 124-131 (2017).
  141. Ichiro Hayakawa, Masami Okamura, Kazuaki Suzuki, Mami Shimanuki, Kizuku Kimura, Takuya Yamada, Takayuki Ohyoshi, and Hideo Kigoshi:
    Total Synthesis of Biselide A, A Cytotoxic Macrolide of Marine Origin,
    Synthesis, 49 (13), 2958-2970 (2017).
  142. Takayuki Ohyoshi, Hikaru Tano, Kei Akemoto, and Hideo Kigoshi:
    Synthetic Studies Toward Aplysiasecosterol a: Construction of the Novel Tricyclic Core,
    Tetrahedron Lett., 58 (33), 3327-3329 (2017).
  143. Ichiro Hayakawa, Kazuaki Suzuki, Masami Okamura, Shota Funakubo, Yuto Onozaki, Dai Kawamura, Takayuki Ohyoshi, and Hideo Kigoshi:
    Total Synthesis of Biselide E, a Marine Polyketide,
    Organic Lett., 19 (20), 5713-5716 (2017).
  144. Masaki Kita, Kota Yamagishi, Kota Tsuchiya, Yu Seguchi, Hiroki Nakane, and Hideo Kigoshi:
    Development of Photoaffinity Derivatives of the Antitumor Macrolide Aplyronine a, a PPI-Inducer Between Actin and Tubulin,
    Bioorg. Med. Chem., 25 (24), 6322-6331 (2017).
  145. Takayuki Ohyoshi, Atsuhiro Takano, Mayu Namiki, Tomotaka Ogura, Yuto Miyazaki, Yuta Ebihara, Koichi Takeno, Ichiro Hayakawa, and Hideo Kigoshi:
    Development of a Novel Inducer of Protein-Protein Interactions Based on Aplyronine A,
    Chem. Commun., 54 (68), 9537-9540 (2018).
  146. Rei Watanabe, Yaping Hu, Keita Iio, Kozo Yoneda, Atsunori Hattori, Atsushi Arai, Hideo Kigoshi, and Masaki Kita:
    Specific Protein-Labeling and Ligand-Binding Position Analysis with Amidopyrene Probes as LDI MS Tags,
    Org. Biomol. Chem., 16 (42), 7883-7890 (2018).
  147. Masaki Kita, Shun Watanabe, Hirotaka Oka, and Hideo Kigoshi:
    Synthesis of the Trisoxazole Macrolactone of Mycalolides via Template-Directed E-Selective Ring-Closing Metathesis,
    Tetrahedron Lett., 59 (41), 3664-3668 (2018).
  148. Atsuhiro Takano, Yiwen Zhao, Takayuki Ohyoshi, and Hideo Kigoshi:
    Synthetic Studies Toward Swinhoeisterol a, a Novel Steroid with an Unusual Carbon Skeleton,
    Tetrahedron Lett., 60 (8), 591-593 (2019).
  149. Takayuki Ohyoshi, Keisuke Mitsugi, Tatsuya Higuma, Fumitaka Ichimura, Masahito Yoshida, and Hideo Kigoshi:
    Concise total syntheses of phelligridins A, C, and D,
    RSC Advances, 9, 7321-7323 (2019).
  150. Menghua Zhang, Taiki Sunaba, Yiting Sun, Kazunori Sasaki, Hiroko Isoda, Hideo Kigoshi, and Masaki Kita:
    Anti-Inflammatory Marine Cyclic Peptide Stylissatin a and Its Derivatives Inhibit Differentiation of Murine Preadipocyte,
    Chem. Commun., 55 (4), 5471-5474 (2019).
  151. Ichiro Hayakawa, Hideo Kigoshi, Shuya Shioda, Takumi Chinen, and Takeo Usui:
    Structure-Activity Relationship Study of Gatastatin Based on the Topliss Tree Approach,
    Heterocycles, 99 (1), 238-247 (2019).
  152. Kentaro Futaki, Momoko Takahashi, Kenta Tanabe, Akari Fujieda, Hideo Kigoshi, and Masaki Kita:
    Synthesis and Biological Activities of Aplyronine a Analogues Toward the Development of Antitumor Protein-Protein Interaction Inducers Between Actin and Tubulin: Conjugation of the C1-C9 Macrolactone Part and the C24-C34 Side Chain,
    ACS Omega, 4 (5), 8598-8613 (2019).
  153. Ichiro Hayakawa, Ryosuke Nagatani, Masaki Ikeda, Dong-eun Yoo, Keita Saito, Hideo Kigoshi, and Akira Sakakura:
    Toward the Synthesis of Yuzurimine-Type Alkaloids: Stereoselective Construction of the Heterocyclic Portions of Deoxyyuzurimine and Macrodaphnine,
    Org. Lett., 21 (16), 6337-6341 (2019).
  154. Takayuki Ohyoshi, Kei Akemoto, Ayaka Taniguchi, Takuma Ishihara, and Hideo Kigoshi:
    Total Synthesis of (-)-Aplaminal by Buchwald-Hartwig Cross-Coupling of an Aminal,
    New J. Chem., 43 (47), 18442-18444 (2019).
  155. Kazunori Sasaki, Yuri Inami, Kenichi Tominaga, Hideo Kigoshi, Takashi Arimura, and Hiroko Isoda:
    Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects,
    Biomed Res. Int., 9584567 (2020). 9 pages
  156. Atsushi Arai, Rei Watanabe, Atsunori Hattori, Keita Iio, Yaping Hu, Kozo Yoneda, Hideo Kigoshi, and Masaki Kita:
    N,N-Dimethylaminopyrene as a fluorescent affinity mass tag for ligand-binding mode analysis,
    Sci. Rep., 10 (1), 7311 (2020). 10 pages
  157. Menghua Zhang, Taiki Sunaba, Yiting Sun, Takahiro Shibata, Kazunori Sasaki, Hiroko Isoda, Hideo Kigoshi, and Masaki Kita:
    Acyl-CoA dehydrogenase long chain (ACADL) is a target protein of stylissatin A, an anti-inflammatory cyclic heptapeptide,
    J. Antibiot., (73), 589-592 (2020).
  158. Minako Hirukawa, Menghua Zhang, Lazaro M. Echenique-Diaz, Koji Mizota, Satoshi D. Ohdachi, Gerardo Begue-Quiala, Jorge L. Delgado-Labanino, Jorgelino Gamez-Diez, Jose Alvarez-Lemus, Leandro Galano Machado, Miguel Suarez Nunez, Takahiro Shibata, Hideo Kigoshi, and Masaki Kita:
    Isolation and structure-activity relationship studies of jacaranones: Anti-inflammatory quinoids from the Cuban endemic plant Jacaranda arborea (Bignoniaceae),
    Tetrahedron Lett., 61 (26), 152005 (2020). 5 pages
  159. Takayuki Ohyoshi, Keisuke Mitsugi, Fumitaka Ichimura, Tatsuya Higuma, Masahito Yoshida, and Hideo Kigoshi:
    Total Synthesis and Structure-Activity Relationship Studies of Phelligridins C and D, and Phellifuropyranone A,
    Bull. Chem. Soc. Jpn., 93 (12), 1540-1551 (2020).
  160. Haruna Ebisu, Kana Shintani, Takumi Chinen, Yoko Nagumo, Shuya Shioda, Taisei Hatanaka, Akira Sakakura, Ichiro Hayakawa, Hideo Kigoshi, and Takeo Usui:
    Dual Inhibition of gamma-Tubulin and Plk1 Induces Mitotic Cell Death,
    Front. Pharmacol., 11, 620185 (2021). 7 pages
  161. Osamu Kutomi, Ryosuke Yamamoto, Keiko Hirose, Katsutoshi Mizuno, Yuuhei Nakagiri, Hiroshi Imai, Akira Noga, Jagan Mohan Obbineni, Noemi Zimmermann, Masako Nakajima, Daisuke Shibata, Misa Shibata, Kogiku Shiba, Masaki Kita, Hideo Kigoshi, Yui Tanaka, Yuya Yamasaki, Yuma Asahina, Chihong Song, Mami Nomura, Mamoru Nomura, Ayako Nakajima, Mia Nakachi, Lixy Yamada, Shiori Nakazawa, Hitoshi Sawada, Kazuyoshi Murata, Kaoru Mitsuoka, Takashi Ishikawa, Ken-ichi Wakabayashi, Takahide Kon, and Kazuo Inaba:
    A dynein-associated photoreceptor protein prevents ciliary acclimation to blue light,
    Sci. Adv., 7 (9), eabf3621 (2021). 9 pages
  162. Takayuki Ohyoshi, Hikaru Tano, and Hideo Kigoshi:
    Synthetic Studies Toward Aplysiasecosterol a: Concise Synthesis of the Tricyclic Core and Its Reactions for Introduction of the D Ring Fragment,
    Bull. Chem. Soc. Jpn., 94 (4), 1179-1184 (2021).
  163. Tetsuya Inaba, Yoshimasa Ishizaki, Masayuki Igarashi, Masahito Yoshida, and Hideo Kigoshi:
    Total Synthesis of Hytramycin V, an Antibiotic Cyclopeptide,
    Bull. Chem. Soc. Jpn., 94 (7), 1922-1930 (2021).
  164. Didik Huswo Utomo, Akari Fujieda, Kentaro Tanaka, Momoko Takahashi, Kentaro Futaki, Kenta Tanabe, Hideo Kigoshi, and Masaki Kita:
    The C29-C34 Parts of Antitumor Macrolide Aplyronine A Serve as Versatile Actin-Affinity Tags,
    Chem. Commun., 57 (9), 10540-10543 (2021).
  165. Tran Ngoc Linh, Takashi Arimura, Kenichi Tominaga, Hideo Kigoshi, and Hiroko Isoda:
    Syntheses and Aggregation Properties of New Squalene Receptors Bearing Open Chain Ligands,
    Supramol. Chem., 33 (5), 194-201 (2021).
  166. Takayuki Ohyoshi, Atsuhiro Takano, Imari Kikuchi, Tomotaka Ogura, Mayu Namiki, Yuto Miyazaki, Takahiro Hirano, Shota Konishi, Yuta Ebihara, Koichi Takeno, Ichiro Hayakawa, and Hideo Kigoshi:
    Structure-Activity Relationship Studies on an Antitumor Marine Macrolide Using Aplyronine A-Swinholide A Hybrid,
    Org. Biomol. Chem., 20 (14), 2922-2938 (2022).
  167. Masahito Yoshida, Tomoya Matsushita, Shinji Kondo, Hiroko Isoda, and Hideo Kigoshi:
    Structure Revision of Trichomide D by Total Synthesis,
    J. Nat. Prod., 85 (7), 1850-1860 (2022).
  168. Keisuke Mitsugi, Toru Takabayashi, Takayuki Ohyoshi, and Hideo Kigoshi:
    Total Synthesis of a PPAP, Nemorosonol, Using a Tandem Michael Addition-Intramolecular Aldol Reaction.,
    Org. Lett., 24 (25), 4635-4639 (2022).
  169. Takayuki Ohyoshi, Yiwen Zhao, Kei Akemoto, Takuma Ishihara, Ayaka Taniguchi, Menghua Zhang, and Hideo Kigoshi:
    Bioinspired Total Synthesis and Structure-Activity Relationship Studies on Aplaminal,
    Bull. Chem. Soc. Jpn., 95 (8), 1242-1249 (2022).
  170. Takayuki Ohyoshi, Yiwen Zhao, and Hideo Kigoshi:
    Isolation and Synthesis of Azuriaplysins A and B, Bromoditerpenes with an alfa-Methylene Carbonyl From the Sea Hare Aplysia kurodai,
    J. Nat. Prod., 85 (8), 2082-2089 (2022).
  171. Takayuki Ohyoshi, Mayu Namiki, Yuto Miyazaki, Shusei Sato, Tomonari Noguchi, and Hideo Kigoshi:
    Toward the Total Synthesis of Scytophycins: Synthesis of the C7-C21 Fragments of Scytophycins A, B, and C,
    Tetrahedron Lett., 114, 154250 (2023). 5 pages
  172. Takayuki Ohyoshi, Hidetada Iizumi, Shu Hosono, Hikaru Tano, and Hideo Kigoshi:
    Total Synthesis of Aplysiasecosterols A and B, Two Marine 9,11-Secosteroids,
    Org. Lett., 25 (25), 4725-4729 (2023).
  173. Masahito Yoshida, Tetsuya Inaba, Yuko Shibuya, Masayuki Igarashi, and Hideo Kigoshi:
    Concise Total Synthesis and Biological Evaluation of Pargamicin A and its Diastereomer, Piperazic Acid-containing Cyclopeptides,
    ChemPlusChem, 88 (8), e202300339 (2023). 6 pages
  174. Masahito Yoshida, Yuhi Okoshi, and Hideo Kigoshi:
    Concise Total Synthesis and Structure Revision of Metacridamides A and B,
    Chem. Commun., 59 (65), 9880-9883 (2023).

著書、総説

  1. 山田靜之, 丹羽治樹, 木越英夫:
    植物起源の発がん物質の合成,
    生体機能解明のための化学合成, 金岡祐一, 後藤俊夫, 芝 哲夫, 中嶋暉躬, 向山光昭共編, 化学増刊 118, 化学同人, pp. 191-201 (1990).
  2. 山田靜之, 木越英夫:
    わらびの究極発癌物質の合成およびDNAとの反応,
    有機合成化学協会誌, 53 (1), 13-21 (1995).
  3. 木越英夫, 山田靜之:
    海洋産抗腫瘍性物質アプリロニンAの立体構造と合成,
    有機合成化学協会誌, 54 (12), 1076-1084 (1996).
  4. Kiyoyuki Yamada and Hideo Kigoshi:
    Bioactive Compounds from the Sea Hares of Two Genera: Aplysia and Dolabella,
    Bull. Chem. Soc. Jpn., 70 (7), 1479-1489 (1997).
  5. Kiyoyuki Yamada, Makoto Ojika, and Hideo Kigoshi:
    Isolation, Chemistry, and Biochemistry of Ptaquiloside, a Bracken Carcinogen,
    Angew. Chem., 110 (13/14), 1918-1926 (1998); Angew. Chem. Int. Ed. Engl., 37 (13/14), 1818-1826 (1998).
  6. 山田靜之, 小鹿 一, 木越英夫, 杉浦幸雄:
    わらび発癌物質:化学研究とDNA修飾,
    蛋白質核酸酵素, 43 (6), 752-761 (1998).
  7. Kiyoyuki Yamada, Makoto Ojika, Hideo Kigoshi, and Kiyotake Suenaga:
    "Cytotoxic Substances from Opisthobranch Mollusks,"
    in "Drugs from the Sea," ed by N. Fusetani, S. Karger AG, Basel, pp. 59-73 (2000).
  8. 木越英夫:
    海洋産抗腫瘍性物質,
    海洋天然物/錯体/コンビナトリアル/全合成(先端化学シリーズV), 丸善, pp. 20-26 (2003).
  9. 木越英夫:
    アクチン脱重合分子の設計と合成,
    海洋天然物/錯体/コンビナトリアル/全合成(先端化学シリーズV), 丸善, pp. 304-311 (2003).
  10. 末永聖武, 木越英夫:
    アクチン脱重合活性海洋天然物の合成と構造活性相関,
    化学工業, 55 (8), 577-582 (2004).
  11. 木越英夫, 末永聖武:
    軟体動物,
    海洋生物成分の利用, 伏谷伸宏監修, シーエムシー出版, pp. 115-131 (2005).
  12. 末永聖武,木越英夫:
    アクチン脱重合分子の合成と活性,
    有機合成化学協会誌, 64 (12), 1273-1281 (2006).
  13. Kiyoyuki Yamada, Makoto Ojika, and Hideo Kigoshi:
    Ptaquiloside, the Major Toxin of Bracken, and Related Terpene Glycosides: Chemistry, Biology and Ecology,
    Nat. Prod. Rep., 24 (4), 798-813 (2007).
  14. 山田靜之, 小鹿 一, 木越英夫:
    発がん物質,
    天然物化学−植物編−, 山村庄亮, 長谷川宏司編, アイピーシー, pp. 161-174 (2007).
  15. 山田靜之, 丹羽治樹, 木越英夫:
    プタキロシン, アニサチン,
    天然物化学−植物編−, 山村庄亮, 長谷川宏司編, アイピーシー, pp. 287-292 (2007).
  16. Hideo Kigoshi and Ichiro Hayakawa:
    Marine Cytotoxic Macrolides Haterumalides and Biselides, and Related Natural Products,
    Chemical Record, 7, 254-264 (2007).
  17. 末永聖武, 木越英夫:
    アクチンに作用する海洋産抗腫瘍性物質アプリロニンAの生物有機化学,
    化学と生物, 45 (9), 611-618 (2007).
  18. 山村庄亮, 長谷川宏司, 木越英夫編:
    天然物化学−海洋生物編−,
    アイピーシー (2008).
  19. Kiyoyuki Yamada, Makoto Ojika, Hideo Kigoshi, and Kiyotake Suenaga:
    Aplyronine A, a Potent Antitumour Macrolide of Marine Origin, and the Congeners Aplyronines B-H: Chemistry and Biology,
    Nat. Prod. Rep., 26 (1), 27-43 (2009).
  20. Kiyoyuki Yamada, Makoto Ojika, Hideo Kigoshi, and Kiyotake Suenaga:
    Cytotoxic Substances from Two Species of Japanese Sea Hares: Chemistry and Bioactivity,
    Proc. Jpn. Acad., Ser. B, 86 (3), 176-189 (2010).
  21. 早川一郎, 木越英夫:
    腫瘍細胞増殖阻害マクロライド ハテルマライドNA, Bの全合成と構造活性相関,
    有機合成化学協会誌, 68 (8), 814-823 (2010).
  22. Masaki Kita and Hideo Kigoshi:
    "Antitumor Effects of Sea Hare-derived Compounds in Cancer." in Handbook of Anticancer Drugs from Marine Origin, Ed. S. -K. Kim (Springer International Publishing Switzerland), pp. 701-740 (2015).
  23. 北将樹、木越英夫:
    光親和性プローブを用いた抗腫瘍性天然物アプリロニンAの標的分子と作用機序の研究,
    有機合成化学協会誌, 73 (2), 151-160 (2015).
  24. 平山裕一郎, 北将樹, 木越英夫:
    海洋産抗腫瘍性物質 アプリロニンAの作用機序,
    化学と生物, 53 (3), 164-170 (2015).
  25. Masaki Kita and Hideo Kigoshi:
    Marine natural products that interfere with multiple cytoskeletal protein interactions,
    Nat. Prod. Rep., 32 (4), 534-542 (2015).
  26. Ichiro Hayakawa and Hideo Kigoshi:
    Recent Progress in the Synthetic Study of an Antitumor Marine Macrolide Aplyronine A and Related Molecules,
    Heterocycles, 91 (6), 1137-1155 (2015).
  27. Takayuki Ohyoshi and Hideo Kigoshi:
    Recent Progress in Structure-Activity Relationship Studies on Antitumor Macrolide Aplyronine a by Using Hybridization of Actin-Depolymerizing Natural Product,
    Chemistry Lett., 50 (4), 580-584 (2021).
  28. 木越英夫編:
    海洋天然物化学(化学の要点シリーズ43),
    日本化学会、共立出版 (2023).

解説・訳本など

  1. 木越英夫:
    天然物化学での最新NMR,
    化学, 56 (9), 28-29 (2001).
  2. 石橋正己, 岩澤伸治, 小田嶋和徳, 金井 求, 木越英夫, 白川英二, 中辻慎一, 橋本俊一, 松原誠次郎, 吉田潤一:
    ウォーレン有機化学(上/下), 野依良治, 奥山 格, 柴崎正勝, 檜山為次郎監訳, 東京化学同人 (2003).
  3. 木越英夫:
    カバは血の色の汗をかく!?,
    化学, 59 (10), 65-66 (2004).
  4. 木越英夫、他24名:
    人名反応に学ぶ有機合成戦略、富岡 清監訳、化学同人(2006).
  5. ソレル有機化学(上/下), 村田道雄、石橋正巳、木越英夫、佐々木誠監訳、東京化学同人 (2009).
  6. 早川一郎, 木越英夫:
    トリトンB(十字路欄),
    有機合成化学協会誌, 68 (8), 870 (2010).
  7. 早川一郎, 木越英夫:
    安藤オレフィン化、Grieco−西沢反応,
    天然物合成で活躍した反応 実験のコツとポイント、有機合成化学協会編、化学同人、pp. 2-3, 24-25 (2011).
  8. 早川一郎, 木越英夫:
    ますます進化する天然物合成−実用的天然物合成の時代が見えてきた(最新のトピックス欄),
    化学, 67 (6), 70-71 (2012).
  9. 金井 求, 木越英夫, 高須清誠, 松永茂樹:
    ウォーレン有機合成:逆合成からのアプローチ, 柴崎正勝, 橋本俊一監訳, 東京化学同人 (2014).
(September 2023)


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